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    ATB BETA Protein phosphatase 2A, regulatory subunit PR55 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838348, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATB BETA
    Official Full Name
    Protein phosphatase 2A, regulatory subunit PR55
    Primary source
    TAIR:AT1G17720
    Locus tag
    AT1G17720
    See related
    Araport:AT1G17720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F11A6.6; F11A6_6
    Summary
    type 2A protein serine/threonine phosphatase 55 kDa B
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    Genomic context

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    See ATB BETA in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Sequence:
    Chromosome: 1; NC_003070.9 (6093185..6098443, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene prenylated RAB acceptor 1.F1 Neighboring gene Pyridoxal phosphate phosphatase-related protein Neighboring gene vacuolar protein sorting 46.1 Neighboring gene uncharacterized protein Neighboring gene D-3-phosphoglycerate dehydrogenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of DNA sequences encoding a novel isoform of the 55 kDa B regulatory subunit of the type 2A protein serine/threonine phosphatase of Arabidopsis thaliana. Corum JW 3rd, et al. Plant Mol Biol, 1996 May. PMID 8756607
    2. B-family subunits of protein phosphatase 2A are necessary for pollen development but not for female gametophyte development in Arabidopsis. Tsugama D, et al. Biochem Biophys Res Commun, 2018 Oct 20. PMID 30243715
    3. Protein phosphatase 2A B55 and A regulatory subunits interact with nitrate reductase and are essential for nitrate reductase activation. Heidari B, et al. Plant Physiol, 2011 May. PMID 21436382, Free PMC Article
    4. ROTUNDA3 function in plant development by phosphatase 2A-mediated regulation of auxin transporter recycling. Karampelias M, et al. Proc Natl Acad Sci U S A, 2016 Mar 8. PMID 26888284, Free PMC Article
    5. Identification of Open Stomata1-Interacting Proteins Reveals Interactions with Sucrose Non-fermenting1-Related Protein Kinases2 and with Type 2A Protein Phosphatases That Function in Abscisic Acid Responses. Waadt R, et al. Plant Physiol, 2015 Sep. PMID 26175513, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data suggest that the B subunit of protein phosphatase 2A (PP2A) ATBA and ATBB play pleiotropic roles in pollen development.
      Title: B-family subunits of protein phosphatase 2A are necessary for pollen development but not for female gametophyte development in Arabidopsis.
    2. Mutants homozygous for mutation in Bbeta and heterozygous for mutation in Balpha revealed a slower activation rate for nitrate reductase (NR) than wild-type plants, pointing to these subunits as part of a PP2A complex responsible for NR dephosphorylation.
      Title: Protein phosphatase 2A B55 and A regulatory subunits interact with nitrate reductase and are essential for nitrate reductase activation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101634.4
    NM_179350.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein phosphatase regulator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein dephosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus HDA PubMed 
    part_of protein phosphatase type 2A complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Protein phosphatase 2A, regulatory subunit PR55
    NP_564033.1
    • ATB BETA; CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain (InterPro:IPR011046), Protein phosphatase 2A, regulatory subunit PR55 (InterPro:IPR000009), Protein phosphatase 2A, regulatory subunit PR55, conserved site (InterPro:IPR018067), WD40 repeat, conserved site (InterPro:IPR019775), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (TAIR:AT1G51690.1); Has 1080 Blast hits to 1028 proteins in 280 species: Archae - 0; Bacteria - 91; Metazoa - 514; Fungi - 212; Plants - 124; Viruses - 0; Other Eukaryotes - 139 (source: NCBI BLink).
    NP_849681.1
    • ATB BETA; CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain (InterPro:IPR011046), Protein phosphatase 2A, regulatory subunit PR55 (InterPro:IPR000009), Protein phosphatase 2A, regulatory subunit PR55, conserved site (InterPro:IPR018067), WD40 repeat, conserved site (InterPro:IPR019775), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (TAIR:AT1G51690.3); Has 1042 Blast hits to 998 proteins in 278 species: Archae - 0; Bacteria - 71; Metazoa - 509; Fungi - 214; Plants - 122; Viruses - 0; Other Eukaryotes - 126 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6093185..6098443 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179350.4 → NP_849681.1  Protein phosphatase 2A, regulatory subunit PR55 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849681.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WIR9, A0A5S9UWK7, A0A654EAU4
      Conserved Domains (2) summary
      COG5170
      Location:17 → 500
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:39 → 85
      7WD40; WD40 repeat [structural motif]

    2. NM_101634.4 → NP_564033.1  Protein phosphatase 2A, regulatory subunit PR55 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564033.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39247, Q9FZ61
      UniProtKB/TrEMBL
      A0A178WKH8, Q0WW19
      Conserved Domains (3) summary
      COG5170
      Location:17 → 501
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:39 → 85
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:37 → 414
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39247.1

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