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    Protein phosphatase 2A regulatory B subunit family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837906, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Protein phosphatase 2A regulatory B subunit family protein
    Primary source
    TAIR:AT1G13460
    Locus tag
    AT1G13460
    See related
    Araport:AT1G13460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T6J4.19; T6J4_19
    Summary
    Encodes protein phosphatase 2A (PP2A) B'theta subunit. Targeted to peroxisomes.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (4615767..4618449)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Homeodomain-like superfamily protein Neighboring gene hypothetical protein (DUF1262) Neighboring gene hypothetical protein (DUF1262)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Protein phosphatase 2A holoenzyme is targeted to peroxisomes by piggybacking and positively affects peroxisomal β-oxidation. Kataya AR, et al. Plant Physiol, 2015 Feb. PMID 25489022, Free PMC Article
    2. Diversity in subcellular targeting of the PP2A B'eta subfamily members. Matre P, et al. Planta, 2009 Oct. PMID 19672620
    3. The Brassinosteroid-Activated BRI1 Receptor Kinase Is Switched off by Dephosphorylation Mediated by Cytoplasm-Localized PP2A B' Subunits. Wang R, et al. Mol Plant, 2016 Jan 4. PMID 26517938
    4. PP2A activates brassinosteroid-responsive gene expression and plant growth by dephosphorylating BZR1. Tang W, et al. Nat Cell Biol, 2011 Feb. PMID 21258370, Free PMC Article
    5. Identification of BZR1-interacting proteins as potential components of the brassinosteroid signaling pathway in Arabidopsis through tandem affinity purification. Wang C, et al. Mol Cell Proteomics, 2013 Dec. PMID 24019147, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_101216.2
    NM_202087.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of brassinosteroid mediated signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of fatty acid beta-oxidation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein phosphatase type 2A complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein phosphatase 2A regulatory B subunit family protein
    NP_172803.1
    • Protein phosphatase 2A regulatory B subunit family protein; FUNCTIONS IN: protein phosphatase type 2A regulator activity; INVOLVED IN: signal transduction; LOCATED IN: peroxisome, protein phosphatase type 2A complex; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2A, regulatory B subunit, B56 (InterPro:IPR002554); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2A regulatory B subunit family protein (TAIR:AT3G26020.2); Has 1181 Blast hits to 1162 proteins in 197 species: Archae - 0; Bacteria - 0; Metazoa - 570; Fungi - 160; Plants - 300; Viruses - 0; Other Eukaryotes - 151 (source: NCBI BLink).
    NP_973816.1
    • Protein phosphatase 2A regulatory B subunit family protein; FUNCTIONS IN: protein phosphatase type 2A regulator activity; INVOLVED IN: signal transduction; LOCATED IN: peroxisome, protein phosphatase type 2A complex; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2A, regulatory B subunit, B56 (InterPro:IPR002554); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2A regulatory B subunit family protein (TAIR:AT3G26020.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      4615767..4618449
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202087.2 → NP_973816.1  Protein phosphatase 2A regulatory B subunit family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973816.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0V836, Q8LF36, Q9FX52
      UniProtKB/TrEMBL
      A0A178WBX5, A0A5S9U9F1, A0A654EAJ4
      Conserved Domains (2) summary
      PLN00122
      Location:389 → 491
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:80 → 483
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    2. NM_101216.2 → NP_172803.1  Protein phosphatase 2A regulatory B subunit family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172803.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0V836, Q8LF36, Q9FX52
      UniProtKB/TrEMBL
      A0A178WBX5, A0A5S9U9F1, A0A654EAJ4
      Conserved Domains (2) summary
      PLN00122
      Location:389 → 491
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:80 → 483
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LF36.2

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