OVA5 Lysyl-tRNA synthetase, class II [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: OVA5
Official Full Name: Lysyl-tRNA synthetase, class II
Primary source: TAIR:AT3G13490
Locus tag: AT3G13490
See related: Araport:AT3G13490
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA LYSYL-TRNA SYNTHETASE 2; ATKRS-2; OVULE ABORTION 5
Summary: Encodes a dual targeted lysyl-tRNA ligase that is found both in the mitochondrion and the chloroplast. Plants mutated in this gene exhibit an ovule abortion phenotype.
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_112195.3

Function	Evidence Code	Pubs
enables lysine-tRNA ligase activity	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in lysyl-tRNA aminoacylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within plant ovule development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed

NP_187958.1

OVULE ABORTION 5 (OVA5); FUNCTIONS IN: aminoacyl-tRNA ligase activity, nucleotide binding, ATP binding, nucleic acid binding, lysine-tRNA ligase activity; INVOLVED IN: tRNA aminoacylation for protein translation, ovule development; LOCATED IN: mitochondrion, chloroplast, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Nucleic acid binding, OB-fold, tRNA/helicase-type (InterPro:IPR004365), Aminoacyl-tRNA synthetase, class II, conserved domain (InterPro:IPR006195), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Aminoacyl-tRNA synthetase, class II (D/K/N) (InterPro:IPR004364), Lysyl-tRNA synthetase, class II, C-terminal (InterPro:IPR018149), Aminoacyl-tRNA synthetase, class II (D/K/N)-like (InterPro:IPR018150), Lysyl-tRNA synthetase, class II (InterPro:IPR002313); BEST Arabidopsis thaliana protein match is: lysyl-tRNA synthetase 1 (TAIR:AT3G11710.1); Has 27489 Blast hits to 22097 proteins in 2943 species: Archae - 404; Bacteria - 18954; Metazoa - 615; Fungi - 809; Plants - 266; Viruses - 0; Other Eukaryotes - 6441 (source: NCBI BLink).