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    TRM11 tRNA modification 11 protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822245, updated on 18-Sep-2024

    Summary

    Official Symbol
    TRM11
    Official Full Name
    tRNA modification 11 protein
    Primary source
    TAIR:AT3G26410
    Locus tag
    AT3G26410
    See related
    Araport:AT3G26410
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTRM11; tRNA modification 11
    Summary
    Encodes a protein involved in modification of nucleosides in tRNA. Mutants have only 7.3% 2-methylguanosine levels of wild type counterparts.
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    Genomic context

    See TRM11 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (9669415..9671348, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 4B1 Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein with retrovirus zinc finger-like domain-containing protein Neighboring gene transmembrane protein, putative (DUF707) Neighboring gene beta-1,4-N-acetylglucosaminyltransferase family protein

    General gene information

    NM_113548.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables tRNA (guanine(10)-N2)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within 2-methylguanosine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within tRNA modification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    tRNA modification 11 protein
    NP_566792.1
    • methyltransferases;nucleic acid binding; FUNCTIONS IN: methyltransferase activity, nucleic acid binding; INVOLVED IN: methylation; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Putative RNA methylase (InterPro:IPR000241), tRNA guanosine-2'-O-methyltransferase, TRM11 (InterPro:IPR016691), DNA methylase, N-6 adenine-specific, conserved site (InterPro:IPR002052); Has 597 Blast hits to 588 proteins in 280 species: Archae - 150; Bacteria - 5; Metazoa - 158; Fungi - 132; Plants - 50; Viruses - 0; Other Eukaryotes - 102 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      9669415..9671348 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113548.5NP_566792.1  tRNA modification 11 protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566792.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V9T8, A0A5S9XFT6, Q9LIN4
      Conserved Domains (1) summary
      COG1041
      Location:1414
      Trm11; tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]