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    MCD1 multiple chloroplast division site 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838675, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MCD1
    Official Full Name
    multiple chloroplast division site 1
    Primary source
    TAIR:AT1G20830
    Locus tag
    AT1G20830
    See related
    Araport:AT1G20830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F2D10.35; F2D10_35; MULTIPLE CHLOROPLAST DIVISION SITE 1
    Summary
    Encodes MCD1 (MULTIPLE CHLOROPLAST DIVISION SITE 1). Determines the site of chloroplast division in concert with MinD (AT5G24020).
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    Genomic context

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    See MCD1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (7242896..7244978)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene tRNA-Trp Neighboring gene tonoplast monosaccharide transporter1 Neighboring gene ncRNA Neighboring gene xylem cysteine peptidase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plant-specific protein MCD1 determines the site of chloroplast division in concert with bacteria-derived MinD. Nakanishi H, et al. Curr Biol, 2009 Jan 27. PMID 19135368
    2. MCD1 Associates with FtsZ Filaments via the Membrane-Tethering Protein ARC6 to Guide Chloroplast Division. Chen L, et al. Plant Cell, 2018 Aug. PMID 29967285, Free PMC Article
    3. Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana. Ferro M, et al. Mol Cell Proteomics, 2003 May. PMID 12766230
    4. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001332470.1
    NM_101936.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chloroplast fission IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within chloroplast fission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast intermembrane space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    multiple chloroplast division site 1
    NP_173507.1
    • MULTIPLE CHLOROPLAST DIVISION SITE 1 (MCD1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: chloroplast fission; LOCATED IN: chloroplast inner membrane, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; Has 38 Blast hits to 38 proteins in 12 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 38; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7242896..7244978
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101936.3 → NP_173507.1  multiple chloroplast division site 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173507.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GWA7, Q9LM68
      UniProtKB/TrEMBL
      A0A5S9VCK6, A0A654EBJ0

    2. NM_001332470.1 → NP_001321244.1  multiple chloroplast division site 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W884, A0A1P8AQD4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GWA7.1

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