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    VHP2;2 Inorganic H pyrophosphatase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838249, updated on 18-Sep-2024

    Summary

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    Official Symbol
    VHP2;2
    Official Full Name
    Inorganic H pyrophosphatase family protein
    Primary source
    TAIR:AT1G16780
    Locus tag
    AT1G16780
    See related
    Araport:AT1G16780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtVHP2;2; F17F16.2; F17F16_2
    Summary
    Encodes a type II H+-PPases that localizes to and function as a proton pump of the Golgi apparatus in most tissues except for mature leaves.
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    Genomic context

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    See VHP2;2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    16
    Sequence:
    Chromosome: 1; NC_003070.9 (5739468..5744636, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene kinase with adenine nucleotide alpha hydrolases-like domain-containing protein Neighboring gene uncharacterized protein Neighboring gene ribosomal protein-like protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene 7-dehydrocholesterol reductase-like protein Neighboring gene vacuolar ATP synthase catalytic subunit-related / V-ATPase-related / vacuolar proton pump-like protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantification, organ-specific accumulation and intracellular localization of type II H(+)-pyrophosphatase in Arabidopsis thaliana. Segami S, et al. Plant Cell Physiol, 2010 Aug. PMID 20605924
    2. Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana. Shimaoka T, et al. Plant Cell Physiol, 2004 Jun. PMID 15215502
    3. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The type II H(+)-PPase functions as a proton pump in the Golgi and related vesicles in young tissues. [AtVHP2;2]
      Title: Quantification, organ-specific accumulation and intracellular localization of type II H(+)-pyrophosphatase in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001332258.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables diphosphate hydrolysis-driven proton transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inorganic diphosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    Inorganic H pyrophosphatase family protein
    NP_001319021.1
    • VHP2;2; FUNCTIONS IN: inorganic diphosphatase activity, hydrogen-translocating pyrophosphatase activity; INVOLVED IN: proton transport; LOCATED IN: Golgi apparatus, vacuole; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Inorganic H+ pyrophosphatase (InterPro:IPR004131); BEST Arabidopsis thaliana protein match is: vacuolar H+-pyrophosphatase 2 (TAIR:AT1G78920.2); Has 6490 Blast hits to 6472 proteins in 788 species: Archae - 67; Bacteria - 1308; Metazoa - 5; Fungi - 1; Plants - 281; Viruses - 0; Other Eukaryotes - 4828 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5739468..5744636 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332260.1 → NP_001323032.1  Inorganic H pyrophosphatase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I4J7, Q9FWR2
      UniProtKB/TrEMBL
      A0A178WMW7, A0A5S9UU28, A0A7G2DU68
      Conserved Domains (1) summary
      PLN02277
      Location:73 → 802
      PLN02277; H(+) -translocating inorganic pyrophosphatase

    2. NM_001332259.1 → NP_001323031.1  Inorganic H pyrophosphatase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I4J7, Q9FWR2
      UniProtKB/TrEMBL
      A0A178WMW7, A0A5S9UU28, A0A7G2DU68
      Conserved Domains (1) summary
      PLN02277
      Location:73 → 802
      PLN02277; H(+) -translocating inorganic pyrophosphatase

    3. NM_001332258.1 → NP_001319021.1  Inorganic H pyrophosphatase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I4J7, Q9FWR2
      UniProtKB/TrEMBL
      A0A178WMW7, A0A5S9UU28, A0A7G2DU68
      Conserved Domains (1) summary
      PLN02277
      Location:73 → 802
      PLN02277; H(+) -translocating inorganic pyrophosphatase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FWR2.1

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