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    SRF3 STRUBBELIG-receptor family 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827941, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SRF3
    Official Full Name
    STRUBBELIG-receptor family 3
    Primary source
    TAIR:AT4G03390
    Locus tag
    AT4G03390
    See related
    Araport:AT4G03390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F4C21.35; F4C21_35; STRUBBELIG-receptor family 3
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    Genomic context

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    See SRF3 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    17
    Sequence:
    Chromosome: 4; NC_003075.7 (1490426..1495214, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Auxin-responsive GH3 family protein Neighboring gene Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The receptor kinase SRF3 coordinates iron-level and flagellin dependent defense and growth responses in plants. Platre MP, et al. Nat Commun, 2022 Aug 1. PMID 35915109, Free PMC Article
    2. Natural variation at Strubbelig Receptor Kinase 3 drives immune-triggered incompatibilities between Arabidopsis thaliana accessions. Alcázar R, et al. Nat Genet, 2010 Dec. PMID 21037570
    3. Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis. Li G, et al. Nat Cell Biol, 2011 May. PMID 21499259
    4. An extracellular network of Arabidopsis leucine-rich repeat receptor kinases. Smakowska-Luzan E, et al. Nature, 2018 Jan 18. PMID 29320478, Free PMC Article
    5. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Variation in disease susceptibility suggests a basis for the molecular patterns of a recent selective sweep detected at the SRF3 locus in central Asian populations.
      Title: Natural variation at Strubbelig Receptor Kinase 3 drives immune-triggered incompatibilities between Arabidopsis thaliana accessions.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_001340445.1
    NM_116577.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within callose deposition in cell wall IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within circadian rhythm IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within multicellular organismal-level iron ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasmodesmatal plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    STRUBBELIG-receptor family 3
    NP_192248.2
    • STRUBBELIG-receptor family 3 (SRF3); FUNCTIONS IN: protein serine/threonine kinase activity, kinase activity, ATP binding; INVOLVED IN: transmembrane receptor protein tyrosine kinase signaling pathway, protein amino acid phosphorylation; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009); BEST Arabidopsis thaliana protein match is: STRUBBELIG-receptor family 1 (TAIR:AT2G20850.1); Has 154480 Blast hits to 110338 proteins in 3974 species: Archae - 96; Bacteria - 13338; Metazoa - 40210; Fungi - 7879; Plants - 76281; Viruses - 315; Other Eukaryotes - 16361 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1490426..1495214 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116577.5 → NP_192248.2  STRUBBELIG-receptor family 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192248.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WS32, Q6R2K3, Q9ZQZ2
      UniProtKB/TrEMBL
      A0A5S9XPJ0, A0A7G2EY75, C0LGQ2
      Conserved Domains (5) summary
      sd00033
      Location:100 → 121
      LRR_RI; leucine-rich repeat [structural motif]
      pfam07714
      Location:491 → 759
      Pkinase_Tyr; Protein tyrosine kinase
      pfam08263
      Location:32 → 72
      LRRNT_2; Leucine rich repeat N-terminal domain
      pfam13855
      Location:121 → 180
      LRR_8; Leucine rich repeat
      cl21453
      Location:491 → 762
      PKc_like; Protein Kinases, catalytic domain

    2. NM_001340445.1 → NP_001329389.1  STRUBBELIG-receptor family 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WS32, Q6R2K3, Q9ZQZ2
      UniProtKB/TrEMBL
      A0A5S9XPJ0, A0A7G2EY75, C0LGQ2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6R2K3.1

    Gene LinkOut

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