EMB269 GTP1/OBG family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: EMB269
Official Full Name: GTP1/OBG family protein
Primary source: TAIR:AT5G18570
Locus tag: AT5G18570
See related: Araport:AT5G18570
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATOBGC; ATOBGL; chloroplastic SAR1; CPSAR1; EMB3138; EMBRYO DEFECTIVE 269; EMBRYO DEFECTIVE 3138; OBG-like protein; T28N17.50; T28N17_50
Summary: Encodes AtObgC, a plant ortholog of bacterial Obg. AtObgC is a chloroplast-targeting GTPase essential for early embryogenesis. Mutations in this locus result in embryo lethality. The protein is dually localized in the stroma and the inner envelope membrane and is involved in thylakoid membrane biogenesis and functions primarily in plastid ribosome biogenesis during chloroplast development.
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_121862.3

Function	Evidence Code	Pubs
enables GTPase activity	IDA Inferred from Direct Assay more info	PubMed
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within chloroplast organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within embryo development ending in seed dormancy	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within embryo development ending in seed dormancy	NAS Non-traceable Author Statement more info
acts_upstream_of_or_within rRNA processing	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to light stimulus	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within thylakoid membrane organization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast inner membrane	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast stroma	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_197358.2

EMBRYO DEFECTIVE 269 (EMB269); FUNCTIONS IN: GTPase activity; INVOLVED IN: response to light stimulus, thylakoid membrane organization, embryo development, embryo development ending in seed dormancy; LOCATED IN: chloroplast, chloroplast stroma, chloroplast inner membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP1/OBG subdomain (InterPro:IPR006169), GTP-binding protein GTP1/OBG, C-terminal (InterPro:IPR015349), GTP1/OBG (InterPro:IPR006073), GTP1/OBG, conserved site (InterPro:IPR006074), GTP-binding protein, HSR1-related (InterPro:IPR002917), GTP-binding protein Obg/CgtA (InterPro:IPR014100); BEST Arabidopsis thaliana protein match is: GTP-binding protein Obg/CgtA (TAIR:AT1G07615.1); Has 23458 Blast hits to 23162 proteins in 3000 species: Archae - 644; Bacteria - 14053; Metazoa - 1121; Fungi - 826; Plants - 464; Viruses - 52; Other Eukaryotes - 6298 (source: NCBI BLink).