U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    BASL breaking of asymmetry in the stomatal lineage [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836209, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    BASL
    Official Full Name
    breaking of asymmetry in the stomatal lineage
    Primary source
    TAIR:AT5G60880
    Locus tag
    AT5G60880
    See related
    Araport:AT5G60880
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; MAE1.13; MAE1_13
    Summary
    Encodes BASL (BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE), a regulator of asymmetric divisions. In asymmetrically dividing stomatal-lineage cells, BASL accumulates in a polarized crescent at the cell periphery before division, and then localizes differentially to the nucleus and a peripheral crescent in self-renewing cells and their sisters after division. Its transcript levels change after inducing MUTE expression in a mute background.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See BASL in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (24488289..24489836, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene RAB GTPase homolog A1F Neighboring gene Regulator of chromosome condensation (RCC1) family protein Neighboring gene myb domain protein 34 Neighboring gene receptor-like protein kinase 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Ectopic BASL Reveals Tissue Cell Polarity throughout Leaf Development in Arabidopsis thaliana. Mansfield C, et al. Curr Biol, 2018 Aug 20. PMID 30100337, Free PMC Article
    2. Fine-scale dissection of the subdomains of polarity protein BASL in stomatal asymmetric cell division. Zhang Y, et al. J Exp Bot, 2016 Sep. PMID 27422992, Free PMC Article
    3. BASL controls asymmetric cell division in Arabidopsis. Dong J, et al. Cell, 2009 Jun 26. PMID 19523675, Free PMC Article
    4. Phosphorylation of the Polarity Protein BASL Differentiates Asymmetric Cell Fate through MAPKs and SPCH. Zhang Y, et al. Curr Biol, 2016 Nov 7. PMID 27746029, Free PMC Article
    5. Molecular profiling of stomatal meristemoids reveals new component of asymmetric cell division and commonalities among stem cell populations in Arabidopsis. Pillitteri LJ, et al. Plant Cell, 2011 Sep. PMID 21963668, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Ectopic induction of the stomatal protein BASL (BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE) reveals a tissue-wide epidermal polarity field in leaves throughout development.
      Title: Ectopic BASL Reveals Tissue Cell Polarity throughout Leaf Development in Arabidopsis thaliana.
    2. BASL polarization leads to elevated nuclear MPK6 signaling and lowered SPCH abundance in one of the two daughter cells. Therefore, two daughter cells are differentiated by BASL polarity-mediated differential suppression of SPCH, which may provide developmental plasticity in plant stem cell asymmetric cell division.
      Title: Phosphorylation of the Polarity Protein BASL Differentiates Asymmetric Cell Fate through MAPKs and SPCH.
    3. fine-scale dissection of the subdomains of polarity in stomatal asymmetric cell division
      Title: Fine-scale dissection of the subdomains of polarity protein BASL in stomatal asymmetric cell division.
    4. a positive-feedback loop between BASL and the MAPK pathway constitutes a polarity module at the cortex. Cortical localization of BASL requires phosphorylation mediated by MPK3/6.
      Title: The BASL polarity protein controls a MAPK signaling feedback loop in asymmetric cell division.
    5. Study identified BASL, a novel regulator of asymmetric divisions in Arabidopsis.
      Title: BASL controls asymmetric cell division in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    NM_001037038.1
    NM_125481.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in asymmetric cell division IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of asymmetric cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within stomatal complex development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    breaking of asymmetry in the stomatal lineage
    NP_001032115.1
    • BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE (BASL); INVOLVED IN: regulation of asymmetric cell division, stomatal complex development, unidimensional cell growth; LOCATED IN: extrinsic to plasma membrane, nucleus; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: 4 anthesis, E expanded cotyledon stage, D bilateral stage; Has 16 Blast hits to 16 proteins in 8 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 3; Plants - 11; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).
    NP_200896.1
    • BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE (BASL); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24488289..24489836 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125481.3 → NP_200896.1  breaking of asymmetry in the stomatal lineage [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200896.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K0I7, Q5BPF3, Q5Q097, Q5Q098, Q9FJG8
      UniProtKB/TrEMBL
      A0A178UC39, A0A5S9YFY4

    2. NM_001037038.1 → NP_001032115.1  breaking of asymmetry in the stomatal lineage [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001032115.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5BPF3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BPF3.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools