U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MC9 metacaspase 9 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830299, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MC9
    Official Full Name
    metacaspase 9
    Primary source
    TAIR:AT5G04200
    Locus tag
    AT5G04200
    See related
    Araport:AT5G04200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtMC9; AtMCP2f; F21E1.120; F21E1_120; MCP2f; metacaspase 2f; metacaspase 9
    Summary
    Encodes a putative metacaspase. Arabidopsis contains three type I MCP genes (MCP1a-c) and six type II MCP genes (MCP2a#Aeif): AtMCP1a/At5g64240, AtMCP1b/At1g02170, AtMCP1c/At4g25110, AtMCP2a/At1g79310, AtMCP2b/At1g79330, AtMCP2c/At1g79320, AtMCP2d/At1g79340, AtMCP2e/At1g16420, AtMCP2f/At5g04200.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MC9 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (1153740..1155040)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Calcium-binding EF-hand family protein Neighboring gene alpha carbonic anhydrase 3 Neighboring gene phytochrome kinase substrate 4 Neighboring gene CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Post mortem function of AtMC9 in xylem vessel elements. Bollhöner B, et al. New Phytol, 2013 Oct. PMID 23834670
    2. Metacaspase activity of Arabidopsis thaliana is regulated by S-nitrosylation of a critical cysteine residue. Belenghi B, et al. J Biol Chem, 2007 Jan 12. PMID 17110382
    3. Serpin1 of Arabidopsis thaliana is a suicide inhibitor for metacaspase 9. Vercammen D, et al. J Mol Biol, 2006 Dec 8. PMID 17028019
    4. Type II metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana cleave substrates after arginine and lysine. Vercammen D, et al. J Biol Chem, 2004 Oct 29. PMID 15326173
    5. The Arabidopsis metacaspase9 degradome. Tsiatsiani L, et al. Plant Cell, 2013 Aug. PMID 23964026, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_120502.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine-type peptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    metacaspase 9
    NP_196040.1
    • metacaspase 9 (MC9); FUNCTIONS IN: cysteine-type peptidase activity; INVOLVED IN: proteolysis; LOCATED IN: apoplast; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Peptidase C14, caspase catalytic (InterPro:IPR011600); BEST Arabidopsis thaliana protein match is: metacaspase 6 (TAIR:AT1G79320.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1153740..1155040
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120502.3 → NP_196040.1  metacaspase 9 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196040.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LCR8, Q9FYE1
      UniProtKB/TrEMBL
      A0A178U6S6, A0A5S9Y1Z3, A0A654FYC3
      Conserved Domains (1) summary
      pfam00656
      Location:10 → 321
      Peptidase_C14; Caspase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FYE1.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools