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    Sfp33A3 Seminal fluid protein 33A3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 8674115, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Sfp33A3provided by FlyBase
    Official Full Name
    Seminal fluid protein 33A3provided by FlyBase
    Primary source
    FLYBASE:FBgn0259964
    Locus tag
    Dmel_CG42474
    See related
    AllianceGenome:FB:FBgn0259964
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG42474; Dmel\CG42474
    Summary
    Predicted to enable enzyme inhibitor activity. Involved in sexual reproduction. Located in extracellular space. [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See Sfp33A3 in Genome Data Viewer
    Location:
    33A3-33A3; 2-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (11839912..11840329)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (11839912..11840329)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phosphodiesterase 1c Neighboring gene long non-coding RNA:CR43937 Neighboring gene antisense RNA:CR43936 Neighboring gene Seminal fluid protein 33A2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantitative Proteomic Analyses of Molecular Mechanisms Associated with Cytoplasmic Incompatibility in Drosophila melanogaster Induced by Wolbachia. Yuan LL, et al. J Proteome Res, 2015 Sep 4. PMID 26220534
    2. Proteomic discovery of previously unannotated, rapidly evolving seminal fluid genes in Drosophila. Findlay GD, et al. Genome Res, 2009 May. PMID 19411605, Free PMC Article
    3. Proteomics reveals novel Drosophila seminal fluid proteins transferred at mating. Findlay GD, et al. PLoS Biol, 2008 Jul 29. PMID 18666829, Free PMC Article
    4. Development of a Clickable Probe for Profiling of Protein Glutathionylation in the Central Cellular Metabolism of E. coli and Drosophila. Feng S, et al. Chem Biol, 2015 Nov 19. PMID 26526100
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables enzyme inhibitor activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sexual reproduction HEP PubMed 
    Component Evidence Code Pubs
    located_in extracellular space HDA PubMed 

    General protein information

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    Preferred Names
    seminal fluid protein 33A3
    Names
    CG42474-PA
    Sfp33A3-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      11839912..11840329
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169488.2 → NP_001162959.1  seminal fluid protein 33A3 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162959.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B4ZJ97, E1JHG2
      Conserved Domains (1) summary
      cd00104
      Location:26 → 65
      KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JHG2 E1JHG2

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