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    Lcp65Ag3 Larval cuticle protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 59159, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lcp65Ag3provided by FlyBase
    Official Full Name
    Larval cuticle proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0086611
    Locus tag
    Dmel_CG18779
    See related
    AllianceGenome:FB:FBgn0086611
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG18779; DmelLcp65Ag3; Dmel\CG18779; g3; Lcp-g3
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be active in chitin-based extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Lcp65Ag3 in Genome Data Viewer
    Location:
    65A6-65A6; 3-16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6130386..6130989, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6123486..6124089, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ets at 65A Neighboring gene long non-coding RNA:CR46001 Neighboring gene antisense RNA:CR46005 Neighboring gene lethal (3) malignant blood neoplasm Neighboring gene Cuticular protein 65Au Neighboring gene Lcp65Ag2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Smoothened antagonist sonidegib affects the development of D. melanogaster larvae via suppression of epidermis formation. Jiang Z, et al. Pestic Biochem Physiol, 2023 Aug. PMID 37532307
    2. A cluster of cuticle protein genes of Drosophila melanogaster at 65A: sequence, structure and evolution. Charles JP, et al. Genetics, 1997 Nov. PMID 9383064, Free PMC Article
    3. Exploring the multilevel hazards of thiamethoxam using Drosophila melanogaster. Li X, et al. J Hazard Mater, 2020 Feb 15. PMID 31630861
    4. Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster. Charles JP, et al. Insect Biochem Mol Biol, 1998 Mar. PMID 9654737
    5. Mitochondrial genomic variation drives differential nuclear gene expression in discrete regions of Drosophila gene and protein interaction networks. Mossman JA, et al. BMC Genomics, 2019 Sep 2. PMID 31477008, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based larval cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of chitin-based larval cuticle ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chitin-based extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chitin-based extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    larval cuticle protein
    Names
    CG18779-PA
    Lcp65Ag3-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6130386..6130989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_144405.2 → NP_652662.1  larval cuticle protein [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652662.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F3YDJ8, Q9I7Q6
      Related
      FBpp0076769
      Conserved Domains (1) summary
      pfam00379
      Location:37 → 92
      Chitin_bind_4; Insect cuticle protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9I7Q6 Q9I7Q6

    Gene LinkOut

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