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    TB16.3 hypothetical protein [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 887239, updated on 6-Oct-2023

    Summary

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    Gene symbol
    TB16.3
    Gene description
    hypothetical protein
    Locus tag
    Rv2185c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (2447066..2447500, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene long-chain-fatty-acid--CoA ligase FadD15

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mycobacterium tuberculosis Rv2185c contributes to nuclear factor-κB activation. Zhang H, et al. Mol Immunol, 2015 Aug. PMID 25771181
    2. Improving sensitivity for serodiagnosis of tuberculosis using TB16.3-echA1 fusion protein. Khurshid S, et al. Tuberculosis (Edinb), 2014 Sep. PMID 25131688
    3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Novel fusion protein TB16.3-echA1 has a potential in serodiagnosis of tuberculosis with improved sensitivity and reliability.
      Title: Improving sensitivity for serodiagnosis of tuberculosis using TB16.3-echA1 fusion protein.
    2. Mycobacterium tuberculosis Rv2185c contributes to NF-kappaB activation.
      Title: Mycobacterium tuberculosis Rv2185c contributes to nuclear factor-κB activation.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    hypothetical protein
    NP_216701.1
    • A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004 PMID:14766927).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      2447066..2447500 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_216701.1 hypothetical protein Rv2185c [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_216701.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A654TZ25
      Conserved Domains (1) summary
      cd07819
      Location:2 → 142
      SRPBCC_2; Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins
    Nucleotide Protein
    Heading Accession and Version

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