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    PE25 PE family protein PE25 [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 885703, updated on 6-Oct-2023

    Summary

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    Gene symbol
    PE25
    Gene description
    PE family protein PE25
    Locus tag
    Rv2431c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (2727967..2728266, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene alkyl hydroperoxide reductase subunit AhpC Neighboring gene alkyl hydroperoxide reductase AphD Neighboring gene PPE family protein PPE41 Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene transmembrane protein Neighboring gene cyclase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Clusters of PE and PPE genes of Mycobacterium tuberculosis are organized in operons: evidence that PE Rv2431c is co-transcribed with PPE Rv2430c and their gene products interact with each other. Tundup S, et al. FEBS Lett, 2006 Feb 20. PMID 16458305
    2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Rv2431c and Rv2430c are transcribed as an operon. Expression of either alone in E. coli limited their localization to the inclusion bodies; when co-expressed, both proteins appeared in the soluble fraction. These two proteins interact with each other.
      Title: Clusters of PE and PPE genes of Mycobacterium tuberculosis are organized in operons: evidence that PE Rv2431c is co-transcribed with PPE Rv2430c and their gene products interact with each other.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    PE family protein PE25
    YP_177882.1
    • Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of ala-, gly-rich proteins

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      2727967..2728266 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_177882.1 PE family protein PE25 [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for YP_177882.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2I7W9L5
      Conserved Domains (1) summary
      pfam00934
      Location:4 → 94
      PE; PE family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    2G38_A.1
    2G38_C.1
    I6X486.1

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