U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    pks15 polyketide synthase [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 887291, updated on 4-Apr-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    pks15
    Gene description
    polyketide synthase
    Locus tag
    Rv2947c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000962.3 (3296350..3297840, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene transposase Neighboring gene insertion sequence element IS1533 transposase Neighboring gene lipoprotein LppX Neighboring gene polyketide synthase Neighboring gene p-hydroxybenzoyl--AMP ligase Neighboring gene chorismate pyruvate-lyase Neighboring gene long-chain-fatty-acid--AMP ligase FadD29

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Characterisation of pks15/1 in clinical isolates of Mycobacterium tuberculosis from Mexico. Zenteno-Cuevas R, et al. Mem Inst Oswaldo Cruz, 2013 Sep. PMID 24037193, Free PMC Article
    2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. results confirm the utility of locus pks15/1 as a molecular marker for identifying Asian lineages of the M. tuberculosis complex.
      Title: Characterisation of pks15/1 in clinical isolates of Mycobacterium tuberculosis from Mexico.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    General protein information

    Go to the top of the page Help
    Preferred Names
    polyketide synthase

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      3296350..3297840 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_217463.1 polyketide synthase [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_217463.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q50469
      Conserved Domains (2) summary
      cd00833
      Location:47 → 467
      PKS; polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or ...
      pfam08990
      Location:17 → 42
      Docking; Erythronolide synthase docking
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P96284.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases