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    Hgh1 HGH1 homolog [ Mus musculus (house mouse) ]

    Gene ID: 59053, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Hgh1provided by MGI
    Official Full Name
    HGH1 homologprovided by MGI
    Primary source
    MGI:MGI:1930628
    See related
    Ensembl:ENSMUSG00000022554 AllianceGenome:MGI:1930628
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Brp16; Fam203a; MNCb-5873; D15Ertd741e
    Summary
    Is expressed in central nervous system and retina. Orthologous to human HGH1 (HGH1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 9.8), ovary adult (RPKM 9.0) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Hgh1 in Genome Data Viewer
    Location:
    15 D3; 15 35.78 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (76253064..76256056)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (76368864..76371854)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene MAF1 homolog, negative regulator of RNA polymerase III Neighboring gene STARR-seq mESC enhancer starr_39052 Neighboring gene WD repeat domain 97 Neighboring gene STARR-positive B cell enhancer ABC_E11592 Neighboring gene STARR-positive B cell enhancer ABC_E1912 Neighboring gene testis-specific serine kinase 5 Neighboring gene maestro heat-like repeat family member 1 Neighboring gene microRNA 6954

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Desai J, et al. Hum Mol Genet, 2006 Apr 15. PMID 16537572
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    4. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein HGH1 homolog
    Names
    brain protein 16
    family with sequence similarity 203, member A
    protein FAM203A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001411930.1 → NP_001398859.1  protein HGH1 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC155074

    2. NM_021555.3 → NP_067530.2  protein HGH1 homolog isoform 1

      See identical proteins and their annotated locations for NP_067530.2

      Status: VALIDATED

      Source sequence(s)
      AC155074
      Consensus CDS
      CCDS27569.1
      UniProtKB/Swiss-Prot
      Q8C3I8, Q9JJF4
      Related
      ENSMUSP00000023213.7, ENSMUST00000023213.8
      Conserved Domains (2) summary
      pfam04063
      Location:120 → 294
      DUF383; Domain of unknown function (DUF383)
      pfam04064
      Location:299 → 351
      DUF384; Domain of unknown function (DUF384)

    RNA

    1. NR_177984.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC155074

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      76253064..76256056
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_384030.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C3I8.1 GenPept UniProtKB/Swiss-Prot:Q8C3I8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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