U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Vcpip1 valosin containing protein (p97)/p47 complex interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 70675, updated on 9-Dec-2024

    Summary

    Official Symbol
    Vcpip1provided by MGI
    Official Full Name
    valosin containing protein (p97)/p47 complex interacting protein 1provided by MGI
    Primary source
    MGI:MGI:1917925
    See related
    Ensembl:ENSMUSG00000045210 AllianceGenome:MGI:1917925
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    VCIP135; mKIAA1850; 4932442A08; 5730421J18Rik; 5730538E15Rik
    Summary
    This gene encodes a deubiquitinating enzyme that interacts with valosin containing protein p97 and plays a role in the assembly of Golgi apparatus during mitosis. [provided by RefSeq, Dec 2014]
    Expression
    Ubiquitous expression in placenta adult (RPKM 3.5), frontal lobe adult (RPKM 3.2) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Vcpip1 in Genome Data Viewer
    Location:
    1 A2; 1 2.08 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (9788847..9818607, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (9718622..9748382, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2610203C22 gene Neighboring gene STARR-seq mESC enhancer starr_00166 Neighboring gene STARR-seq mESC enhancer starr_00167 Neighboring gene vexin Neighboring gene VISTA enhancer mm1546 Neighboring gene myeloblastosis oncogene-like 1 Neighboring gene STARR-seq mESC enhancer starr_00168 Neighboring gene RIKEN cDNA 1700034P13 gene Neighboring gene STARR-positive B cell enhancer ABC_E7714 Neighboring gene STARR-seq mESC enhancer starr_00169 Neighboring gene STARR-seq mESC enhancer starr_00171 Neighboring gene STARR-positive B cell enhancer ABC_E7715 Neighboring gene predicted gene, 39590 Neighboring gene translation machinery-associated protein 7 pseudogene Neighboring gene predicted pseudogene 6195 Neighboring gene serum/glucocorticoid regulated kinase 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cysteine-type deubiquitinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables cysteine-type deubiquitinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in DNA damage response ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in DNA damage response ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in Golgi reassembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in Golgi reassembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endoplasmic reticulum membrane fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endoplasmic reticulum membrane fusion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K11-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K11-linked deubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein K48-linked deubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K48-linked deubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein deubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein deubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein-DNA covalent cross-linking repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein-DNA covalent cross-linking repair ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein-DNA covalent cross-linking repair ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of protein localization to chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of protein localization to chromatin ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in Golgi stack IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    deubiquitinating protein VCPIP1
    Names
    VCP/p47 complex-interacting 135-kDa protein
    deubiquitinating protein VCIP135
    valosin-containing protein p97/p47 complex-interacting protein p135
    NP_775619.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173443.3NP_775619.2  deubiquitinating protein VCPIP1

      See identical proteins and their annotated locations for NP_775619.2

      Status: REVIEWED

      Source sequence(s)
      AC158790, BC059209
      Consensus CDS
      CCDS14814.1
      UniProtKB/Swiss-Prot
      Q7TMU9, Q8BP90, Q8CDG3
      UniProtKB/TrEMBL
      A0A0R4J0M9
      Related
      ENSMUSP00000051248.7, ENSMUST00000057438.7
      Conserved Domains (1) summary
      cl19932
      Location:214354
      OTU; OTU-like cysteine protease

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      9788847..9818607 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)