U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG5906 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39343, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG5906provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036217
    Locus tag
    Dmel_CG5906
    See related
    AllianceGenome:FB:FBgn0036217
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT16953; Dmel\CG5906
    Summary
    Predicted to enable monoatomic ion channel activity. Predicted to be involved in mitochondrial ribosome assembly and monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Orthologous to human MPV17L2 (MPV17 mitochondrial inner membrane protein like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG5906 in Genome Data Viewer
    Location:
    68E2-68E2; 3-37 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11870457..11871305, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11863557..11864405, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Coiled-coil domain containing protein 151 Neighboring gene Spermitin

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A Drosophila model of the neurological symptoms in Mpv17-related diseases. Kodani A, et al. Sci Rep, 2022 Dec 31. PMID 36587049, Free PMC Article
    2. Drosophila Mpv17 forms an ion channel and regulates energy metabolism. Corrà S, et al. iScience, 2023 Oct 20. PMID 37810222, Free PMC Article
    3. Genome-wide analysis in Drosophila reveals diet-by-gene interactions and uncovers diet-responsive genes. Francis D, et al. G3 (Bethesda), 2021 Sep 27. PMID 34568906, Free PMC Article
    4. Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. Weber AL, et al. PLoS One, 2012. PMID 22496853, Free PMC Article
    5. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables monoatomic ion channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial ribosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in monoatomic ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG5906-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11870457..11871305 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140261.2 → NP_648518.1  uncharacterized protein Dmel_CG5906 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648518.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZB1, Q9VTQ1
      Related
      FBpp0075803
      Conserved Domains (1) summary
      pfam04117
      Location:122 → 185
      Mpv17_PMP22; Mpv17 / PMP22 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MZB1 Q8MZB1
    Q9VTQ1 Q9VTQ1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools