lectin-37Da lectin-37Da [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: lectin-37Daprovided by FlyBase
Official Full Name: lectin-37Daprovided by FlyBase
Primary source: FLYBASE:FBgn0053532
Locus tag: Dmel_CG33532
See related: AllianceGenome:FB:FBgn0053532
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: AC 007082B; AC007082b; CG33532; CG9978; DL2; Dmel\CG33532
Summary: Enables galactose binding activity. Involved in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; encapsulation of foreign target; and melanization defense response. Located in extracellular region. Is expressed in several structures, including Malpighian tubule; cuticle; embryonic/larval fat body; midgut; and somatic muscle cell. Orthologous to human CLEC6A (C-type lectin domain containing 6A); CLEC4D (C-type lectin domain family 4 member D); and CLEC4E (C-type lectin domain family 4 member E). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (19418317..19419029)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (19418317..19419029)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables carbohydrate binding	IBA Inferred from Biological aspect of Ancestor more info
enables galactose binding	IDA Inferred from Direct Assay more info	PubMed
enables galactose binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables pattern recognition receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IDA Inferred from Direct Assay more info	PubMed
involved_in encapsulation of foreign target	IDA Inferred from Direct Assay more info	PubMed
involved_in immune response	IBA Inferred from Biological aspect of Ancestor more info
involved_in melanization defense response	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular region	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular region	ISM Inferred from Sequence Model more info	PubMed

Names: CG33532-PA; CG33532-PB; Lectin-37 Da; drosophila lectin 2; lectin; lectin-37Da-PA; lectin-37Da-PB

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The following sections contain reference sequences that belong to a specific genome build. Explain