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    l(2)k09913 lethal (2) k09913 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37661, updated on 9-Dec-2024

    Summary

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    Official Symbol
    l(2)k09913provided by FlyBase
    Official Full Name
    lethal (2) k09913provided by FlyBase
    Primary source
    FLYBASE:FBgn0021979
    Locus tag
    Dmel_CG3082
    See related
    AllianceGenome:FB:FBgn0021979
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    1(2)k09913; CG3082; Dmel\CG3082
    Summary
    Enables serine hydrolase activity. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut primordium; head epidermis primordium; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See l(2)k09913 in Genome Data Viewer
    Location:
    59C3-59C3; 2-102 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23067196..23071875)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18954719..18959398)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Prophenoloxidase 3 Neighboring gene transfer RNA:Serine-TGA 1-1 Neighboring gene transfer RNA:Serine-TGA 2-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation of gene sets affected specifically by polyglutamine expression: implication of the TOR signaling pathway in neurodegeneration. Nelson B, et al. Cell Death Differ, 2005 Aug. PMID 15861189
    2. Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body. Juhász G, et al. Cell Death Differ, 2007 Jun. PMID 17363962, Free PMC Article
    3. Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. Dottorini T, et al. BMC Bioinformatics, 2011 Jan 26. PMID 21269436, Free PMC Article
    4. Selection for cold resistance alters gene transcript levels in Drosophila melanogaster. Telonis-Scott M, et al. J Insect Physiol, 2009 Jun. PMID 19232407
    5. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine hydrolase activity HDA PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    lethal (2) k09913
    Names
    CG3082-PA
    CG3082-PB
    CG3082-PC
    CG3082-PD
    CG3082-PE
    CG3082-PF
    CG3082-PG
    CG3082-PH
    CG3082-PI
    l(2)k09913-PA
    l(2)k09913-PB
    l(2)k09913-PC
    l(2)k09913-PD
    l(2)k09913-PE
    l(2)k09913-PF
    l(2)k09913-PG
    l(2)k09913-PH
    l(2)k09913-PI

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23067196..23071875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166583.2 → NP_726285.1  lethal (2) k09913, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726285.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K274
      Related
      FBpp0071869
      Conserved Domains (1) summary
      pfam05705
      Location:146 → 372
      DUF829; Eukaryotic protein of unknown function (DUF829)

    2. NM_001299826.1 → NP_001286755.1  lethal (2) k09913, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286755.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LG95
      Conserved Domains (1) summary
      pfam05705
      Location:145 → 371
      DUF829; Eukaryotic protein of unknown function (DUF829)

    3. NM_001299827.1 → NP_001286756.1  lethal (2) k09913, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286756.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LGC6
      Conserved Domains (1) summary
      pfam05705
      Location:45 → 271
      DUF829; Eukaryotic protein of unknown function (DUF829)

    4. NM_137907.3 → NP_611751.1  lethal (2) k09913, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611751.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K274
      Related
      FBpp0071871
      Conserved Domains (1) summary
      pfam05705
      Location:146 → 372
      DUF829; Eukaryotic protein of unknown function (DUF829)

    5. NM_166582.2 → NP_726284.1  lethal (2) k09913, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726284.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K274
      Related
      FBpp0071870
      Conserved Domains (1) summary
      pfam05705
      Location:146 → 372
      DUF829; Eukaryotic protein of unknown function (DUF829)

    6. NM_001299825.1 → NP_001286754.1  lethal (2) k09913, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286754.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K274
      Conserved Domains (1) summary
      pfam05705
      Location:146 → 372
      DUF829; Eukaryotic protein of unknown function (DUF829)

    7. NM_166584.2 → NP_726286.1  lethal (2) k09913, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726286.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MLS7
      Related
      FBpp0071872
      Conserved Domains (1) summary
      pfam05705
      Location:73 → 299
      DUF829; Eukaryotic protein of unknown function (DUF829)

    8. NM_001299828.1 → NP_001286757.1  lethal (2) k09913, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286757.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LGC6
      Conserved Domains (1) summary
      pfam05705
      Location:45 → 271
      DUF829; Eukaryotic protein of unknown function (DUF829)

    9. NM_001299829.1 → NP_001286758.1  lethal (2) k09913, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286758.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LGC6
      Conserved Domains (1) summary
      pfam05705
      Location:45 → 271
      DUF829; Eukaryotic protein of unknown function (DUF829)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LG95 A0A0B4LG95
    A0A0B4LGC6 A0A0B4LGC6
    Q7K274 Q7K274
    Q8MLS7 Q8MLS7

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