U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Argk1 Arginine kinase 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39041, updated on 9-Dec-2024

    Summary

    Official Symbol
    Argk1provided by FlyBase
    Official Full Name
    Arginine kinase 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0000116
    Locus tag
    Dmel_CG32031
    See related
    AllianceGenome:FB:FBgn0000116
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AK; AK-1; AK1; argk; argK; Argk; ArgK; ARK; CG32031; CG4929; CG5173; Dmel\CG32031; KARG
    Summary
    Predicted to enable arginine kinase activity and creatine kinase activity. Predicted to be involved in phosphorylation. Located in cytosol; extracellular region; and plasma membrane. Is expressed in several structures, including adult head; adult heart; brain; follicle cell; and larval muscle cell. Orthologous to several human genes including CKMT1A (creatine kinase, mitochondrial 1A); CKMT1B (creatine kinase, mitochondrial 1B); and CKMT2 (creatine kinase, mitochondrial 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Argk1 in Genome Data Viewer
    Location:
    66F3-66F4; 3-28 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9048781..9066027, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9041881..9059127, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Dorsocross1 Neighboring gene Arginine kinase 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables arginine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables creatine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables creatine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in phosphocreatine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    arginine kinase 1
    Names
    Argk1-PA
    Argk1-PB
    Argk1-PC
    Argk1-PD
    Argk1-PE
    Argk1-PG
    Argk1-PH
    CG32031-PA
    CG32031-PB
    CG32031-PC
    CG32031-PD
    CG32031-PE
    CG32031-PG
    CG32031-PH
    arginine kinase
    insect intestinal mucin iim22
    NP_001097555.1
    NP_001097556.2
    NP_001286989.1
    NP_523988.2
    NP_729446.1
    NP_729447.1
    NP_729448.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9048781..9066027 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300060.1NP_001286989.1  arginine kinase 1, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286989.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48610, Q8IQB9, Q8IQC0, Q8T0S2, Q9VST5, Q9VST6
      UniProtKB/TrEMBL
      A8JNP1
      Conserved Domains (1) summary
      cd07932
      Location:9356
      arginine_kinase_like; Phosphagen (guanidino) kinases such as arginine kinase and similar enzymes
    2. NM_168312.3NP_729447.1  arginine kinase 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729447.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48610
      Related
      FBpp0076271
      Conserved Domains (1) summary
      cd07932
      Location:85432
      arginine_kinase_like; Phosphagen (guanidino) kinases such as arginine kinase and similar enzymes
    3. NM_168313.4NP_729448.1  arginine kinase 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729448.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48610
      Related
      FBpp0076273
      Conserved Domains (1) summary
      cd07932
      Location:49396
      arginine_kinase_like; Phosphagen (guanidino) kinases such as arginine kinase and similar enzymes
    4. NM_001104085.2NP_001097555.1  arginine kinase 1, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097555.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JNP2
      Conserved Domains (1) summary
      cd07932
      Location:28375
      arginine_kinase_like; Phosphagen (guanidino) kinases such as arginine kinase and similar enzymes
    5. NM_168311.3NP_729446.1  arginine kinase 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729446.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48610
      Related
      FBpp0076270
      Conserved Domains (1) summary
      cd07932
      Location:215562
      arginine_kinase_like; Phosphagen (guanidino) kinases such as arginine kinase and similar enzymes
    6. NM_079264.3NP_523988.2  arginine kinase 1, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523988.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48610, Q8IQB9, Q8IQC0, Q8T0S2, Q9VST5, Q9VST6
      UniProtKB/TrEMBL
      A8JNP1
      Related
      FBpp0076272
      Conserved Domains (1) summary
      cd07932
      Location:9356
      arginine_kinase_like; Phosphagen (guanidino) kinases such as arginine kinase and similar enzymes
    7. NM_001104086.2NP_001097556.2  arginine kinase 1, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097556.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48610, Q8IQB9, Q8IQC0, Q8T0S2, Q9VST5, Q9VST6
      UniProtKB/TrEMBL
      A8JNP1
      Conserved Domains (1) summary
      cd07932
      Location:9356
      arginine_kinase_like; Phosphagen (guanidino) kinases such as arginine kinase and similar enzymes