Polr2L RNA polymerase II, I and III subunit L [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Polr2Lprovided by FlyBase
Official Full Name: RNA polymerase II, I and III subunit Lprovided by FlyBase
Primary source: FLYBASE:FBgn0039218
Locus tag: Dmel_CG13628
See related: AllianceGenome:FB:FBgn0039218
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:SD08670; CG13628; Dmel\CG13628; Rpb10; RPB10
Summary: Predicted to enable zinc ion binding activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase I; and transcription by RNA polymerase II. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Orthologous to human POLR2L (RNA polymerase II, I and III subunit L). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (24717511..24717998)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (20543233..20543720)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-directed 5'-3' RNA polymerase activity	IEA Inferred from Electronic Annotation more info
contributes_to DNA-directed 5'-3' RNA polymerase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
contributes_to RNA polymerase I activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to RNA polymerase I activity	ISS Inferred from Sequence or Structural Similarity more info
contributes_to RNA polymerase II activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to RNA polymerase II activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
contributes_to RNA polymerase III activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to RNA polymerase III activity	ISS Inferred from Sequence or Structural Similarity more info
enables zinc ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in tRNA transcription by RNA polymerase III	IBA Inferred from Biological aspect of Ancestor more info
involved_in tRNA transcription by RNA polymerase III	ISS Inferred from Sequence or Structural Similarity more info
involved_in transcription by RNA polymerase I	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase I	ISS Inferred from Sequence or Structural Similarity more info
involved_in transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
part_of RNA polymerase I complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase I complex	ISS Inferred from Sequence or Structural Similarity more info
part_of RNA polymerase II, core complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase II, core complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of RNA polymerase III complex	IBA Inferred from Biological aspect of Ancestor more info
part_of RNA polymerase III complex	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain