U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Dim1 Dim1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33645, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Dim1provided by FlyBase
    Official Full Name
    Dim1provided by FlyBase
    Primary source
    FLYBASE:FBgn0031601
    Locus tag
    Dmel_CG3058
    See related
    AllianceGenome:FB:FBgn0031601
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE13747; CG3058; Dmel\CG3058; U5-15kD
    Summary
    Predicted to be involved in mRNA splicing, via spliceosome. Part of precatalytic spliceosome. Is expressed in organism. Human ortholog(s) of this gene implicated in Burn-McKeown syndrome. Orthologous to human TXNL4A (thioredoxin like 4A). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Dim1 in Genome Data Viewer
    Location:
    24F1-24F1; 2-12 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4403251..4403955)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4403251..4403955)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene lethal (2) k05819 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Tryptophan-CCA 2-1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Expression of human PQBP-1 in Drosophila impairs long-term memory and induces abnormal courtship. Yoshimura N, et al. FEBS Lett, 2006 Apr 17. PMID 16597440
    2. The splicing co-factor Barricade/Tat-SF1 is required for cell cycle and lineage progression in Drosophila neural stem cells. Abramczuk MK, et al. Development, 2017 Nov 1. PMID 28935704
    3. The Output of Protein-Coding Genes Shifts to Circular RNAs When the Pre-mRNA Processing Machinery Is Limiting. Liang D, et al. Mol Cell, 2017 Dec 7. PMID 29174924, Free PMC Article
    4. A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila. Ashton-Beaucage D, et al. PLoS Biol, 2014 Mar. PMID 24643257, Free PMC Article
    5. Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells. Parkhitko AA, et al. PLoS Genet, 2021 Feb. PMID 33591981, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U4/U6 x U5 tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of precatalytic spliceosome HDA PubMed 
    part_of small nuclear ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Dim1
    Names
    CG3058-PA
    Dim1-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4403251..4403955
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134986.3 → NP_608830.3  Dim1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608830.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZ87, Q9VQZ2
      Related
      FBpp0077125
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZ87 Q8SZ87

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous