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    CG9577 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33016, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9577provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031092
    Locus tag
    Dmel_CG9577
    See related
    AllianceGenome:FB:FBgn0031092
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9577; Ech1; ECH1
    Summary
    Predicted to enable delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity. Predicted to be located in peroxisome. Predicted to be active in mitochondrion. Is expressed in several structures, including adult head; adult heart; cuboidal/columnar epithelium; gut section; and larval muscle system. Orthologous to human ECH1 (enoyl-CoA hydratase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9577 in Genome Data Viewer
    Location:
    19C1-19C1; 1-64 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20166673..20168080)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20060706..20062113)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Rab35 Neighboring gene PHD finger protein 7 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Annexin B10 Neighboring gene Sperm-specific dynein intermediate chain 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. O-GlcNAcylation of boundary element associated factor (BEAF 32) in Drosophila melanogaster correlates with active histone marks at the promoters of its target genes. De D, et al. Nucleus, 2018 Jan 1. PMID 28910574, Free PMC Article
    2. miR-125-chinmo pathway regulates dietary restriction-dependent enhancement of lifespan in Drosophila. Pandey M, et al. Elife, 2021 Jun 8. PMID 34100717, Free PMC Article
    3. The Stearoyl-CoA Desaturase-1 (Desat1) in Drosophila cooperated with Myc to Induce Autophagy and Growth, a Potential New Link to Tumor Survival. Paiardi C, et al. Genes (Basel), 2017 Apr 28. PMID 28452935, Free PMC Article
    4. Drosophila HNF4 regulates lipid mobilization and beta-oxidation. Palanker L, et al. Cell Metab, 2009 Mar. PMID 19254568, Free PMC Article
    5. Dynamics of nuclear matrix proteome during embryonic development in Drosophila melanogaster. Varma P, et al. J Biosci, 2011 Aug. PMID 21799256

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in peroxisome ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9577-PA
    NP_608375.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      20166673..20168080
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134531.4 → NP_608375.1  uncharacterized protein Dmel_CG9577 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608375.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZ25, Q9W5W8
      Related
      FBpp0070006
      Conserved Domains (2) summary
      PRK05617
      Location:54 → 309
      PRK05617; 3-hydroxyisobutyryl-CoA hydrolase; Provisional
      cl23717
      Location:52 → 310
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W5W8 Q9W5W8

    Gene LinkOut

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