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    Lint-O L(3)mbt interactor in ovarian somatic cells [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31254, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lint-Oprovided by FlyBase
    Official Full Name
    L(3)mbt interactor in ovarian somatic cellsprovided by FlyBase
    Primary source
    FLYBASE:FBgn0024993
    Locus tag
    Dmel_CG2662
    See related
    AllianceGenome:FB:FBgn0024993
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2662; Dmel\CG2662; EG:100G10.6; MAD; snuts
    Summary
    Enables chromatin binding activity. Involved in regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. Is active in nucleus. Is expressed in several structures, including antennal primordium; anterior endoderm; embryonic/larval midgut primordium; head epidermis primordium; and mesoderm. Orthologous to human SAMD1 (sterile alpha motif domain containing 1) and SAMD13 (sterile alpha motif domain containing 13). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Lint-O in Genome Data Viewer
    Location:
    3B2-3B2; 1-1.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2698701..2701033)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2592734..2595066)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene period Neighboring gene daywake Neighboring gene Paraplegin Neighboring gene UDP-galactose transporter Neighboring gene eukaryotic translation initiation factor 2B subunit beta Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chromatin binding  
    enables chromatin binding PubMed 
    enables histone binding  
    Component Evidence Code Pubs
    part_of PRC1 complex  
    part_of RNA polymerase II transcription regulator complex PubMed 
    is_active_in nucleus  
    is_active_in nucleus PubMed 

    General protein information

    Preferred Names
    L(3)mbt interactor in ovarian somatic cells
    Names
    CG2662-PA
    CG2662-PB
    L(3)mbt interactor in OSCs
    Lint-O-PA
    Lint-O-PB
    shrunken nuts

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2698701..2701033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297903.1 → NP_001284832.1  L(3)mbt interactor in ovarian somatic cells, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284832.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76866, Q9W4W7
      Conserved Domains (3) summary
      cd09583
      Location:371 → 438
      SAM_Atherin-like; SAM domain of Atherin/Atherin-like subfamily
      smart00454
      Location:371 → 436
      SAM; Sterile alpha motif
      smart00249
      Location:189 → 236
      PHD; PHD zinc finger
    2. NM_130662.3 → NP_570018.1  L(3)mbt interactor in ovarian somatic cells, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_570018.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76866, Q9W4W7
      Related
      FBpp0070456
      Conserved Domains (3) summary
      cd09583
      Location:371 → 438
      SAM_Atherin-like; SAM domain of Atherin/Atherin-like subfamily
      smart00454
      Location:371 → 436
      SAM; Sterile alpha motif
      smart00249
      Location:189 → 236
      PHD; PHD zinc finger
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