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    Ets98B Ets at 98B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43334, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ets98Bprovided by FlyBase
    Official Full Name
    Ets at 98Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0005659
    Locus tag
    Dmel_CG5583
    See related
    AllianceGenome:FB:FBgn0005659
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5583; D-ets-4; D-Ets-4; D-ets4; Dmel\CG5583; Ets; Ets4; ETS4; ets98B
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including embryonic anal pad; embryonic dorsal epidermis; embryonic head epidermis; embryonic ventral epidermis; and gut section. Orthologous to human SPDEF (SAM pointed domain containing ETS transcription factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ets98B in Genome Data Viewer
    Location:
    98B2-98B2; 3-94 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27736538..27748366)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (23562260..23574088)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene barentsz Neighboring gene Carnitine O-octanoyltransferase Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 98a pseudogene Neighboring gene Odorant receptor 98a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Developmental expression pattern of D-ets4, the Drosophila homologue of human Pdef. Hsouna A, et al. Gene Expr Patterns, 2004 Dec. PMID 15567727
    2. Isolation and characterization of five Drosophila genes that encode an ets-related DNA binding domain. Chen T, et al. Dev Biol, 1992 May. PMID 1577186
    3. The Ets family of transcription factors. Wasylyk B, et al. Eur J Biochem, 1993 Jan 15. PMID 8425553
    4. The Density of Regulatory Information Is a Major Determinant of Evolutionary Constraint on Noncoding DNA in Drosophila. Sabarís G, et al. Mol Biol Evol, 2024 Feb 1. PMID 38364113, Free PMC Article
    5. Sequence and functional properties of Ets genes in the model organism Drosophila. Hsu T, et al. Oncogene, 2000 Dec 18. PMID 11175357

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Ets at 98B
    Names
    CG5583-PA
    CG5583-PB
    Ets98B-PA
    Ets98B-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      27736538..27748366
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079811.4 → NP_524535.2  Ets at 98B, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524535.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P29775, Q9VB00
      UniProtKB/TrEMBL
      B7FNJ4, Q29QW5
      Related
      FBpp0084594
      Conserved Domains (2) summary
      cd08532
      Location:264 → 345
      SAM_PNT-PDEF-like; Sterile alpha motif (SAM)/Pointed domain of prostate-derived ETS factor
      smart00413
      Location:429 → 517
      ETS; erythroblast transformation specific domain

    2. NM_001300641.1 → NP_001287570.1  Ets at 98B, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287570.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LHS8, Q29QW5
      Conserved Domains (2) summary
      cd08532
      Location:250 → 331
      SAM_PNT-PDEF-like; Sterile alpha motif (SAM)/Pointed domain of prostate-derived ETS factor
      smart00413
      Location:415 → 503
      ETS; erythroblast transformation specific domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LHS8 A0A0B4LHS8
    P29775.3 P29775

    Gene LinkOut

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