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    CG17036 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34679, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17036provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032449
    Locus tag
    Dmel_CG17036
    See related
    AllianceGenome:FB:FBgn0032449
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17036
    Summary
    Predicted to enable vitamin transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in organism. Human ortholog(s) of this gene implicated in several diseases, including abdominal aortic aneurysm; biotin-responsive basal ganglia disease; cleft lip; dextro-looped transposition of the great arteries; and megaloblastic anemia. Orthologous to several human genes including SLC19A1 (solute carrier family 19 member 1) and SLC19A2 (solute carrier family 19 member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17036 in Genome Data Viewer
    Location:
    33F3-33F3; 2-47 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12698918..12700746, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12698918..12700746, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Intraflagellar transport 43 Neighboring gene Protein interacting with C kinase 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene spichthyin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Glial solute carrier transporters in Drosophila and mice. Featherstone DE. Glia, 2011 Sep. PMID 21732427
    2. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204
    3. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article
    4. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables vitamin transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vitamin transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17036-PA
    CG17036-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      12698918..12700746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135740.3 → NP_609584.1  uncharacterized protein Dmel_CG17036, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609584.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9UNH7, Q9VK64
      Related
      FBpp0079989
      Conserved Domains (1) summary
      pfam01770
      Location:2 → 395
      Folate_carrier; Reduced folate carrier

    2. NM_001298953.1 → NP_001285882.1  uncharacterized protein Dmel_CG17036, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285882.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9UNH7, Q9VK64
      Conserved Domains (1) summary
      pfam01770
      Location:2 → 395
      Folate_carrier; Reduced folate carrier
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VK64 Q9VK64

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