U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG5532 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37761, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG5532provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034902
    Locus tag
    Dmel_CG5532
    See related
    AllianceGenome:FB:FBgn0034902
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5532
    Summary
    Predicted to be involved in regulation of heme biosynthetic process. Predicted to be located in membrane. Predicted to be active in mitochondrial membrane. Is expressed in several structures, including adult head; amnioserosa; anlage in statu nascendi; central brain anlage in statu nascendi; and embryonic/larval midgut primordium. Orthologous to several human genes including TMEM14C (transmembrane protein 14C). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG5532 in Genome Data Viewer
    Location:
    59F7-59F7; 2-104 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23752754..23753515)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19640277..19641038)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene sol narae Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Dutta D, et al. Proc Natl Acad Sci U S A, 2024 Feb 27. PMID 38381787, Free PMC Article
    2. Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity. Upadhyay A, et al. Mol Neurodegener, 2023 Sep 14. PMID 37710351, Free PMC Article
    3. Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. Dottorini T, et al. BMC Bioinformatics, 2011 Jan 26. PMID 21269436, Free PMC Article
    4. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
    5. Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis. Lin WH, et al. Dis Model Mech, 2017 Feb 1. PMID 28067623, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of heme biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG5532-PA
    CG5532-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23752754..23753515
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299852.1 → NP_001286781.1  uncharacterized protein Dmel_CG5532, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286781.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9W1K0
      UniProtKB/TrEMBL
      A0A0B4LGA1
      Conserved Domains (1) summary
      pfam03647
      Location:5 → 94
      Tmemb_14; Transmembrane proteins 14C

    2. NM_137982.4 → NP_611826.1  uncharacterized protein Dmel_CG5532, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611826.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9W1K0
      UniProtKB/TrEMBL
      A0A0B4LGA1
      Related
      FBpp0072000
      Conserved Domains (1) summary
      pfam03647
      Location:5 → 94
      Tmemb_14; Transmembrane proteins 14C
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LGA1 A0A0B4LGA1
    Q9W1K0.1 Q9W1K0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools