U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MFS18 Major Facilitator Superfamily Transporter 18 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33650, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MFS18provided by FlyBase
    Official Full Name
    Major Facilitator Superfamily Transporter 18provided by FlyBase
    Primary source
    FLYBASE:FBgn0025684
    Locus tag
    Dmel_CG15438
    See related
    AllianceGenome:FB:FBgn0025684
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:CK02623; CG15438; CK02623; Dmel\CG15438
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in ATP transport. Is expressed in adult head. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human SLC17A9 (solute carrier family 17 member 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MFS18 in Genome Data Viewer
    Location:
    24F2-24F3; 2-12 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4446670..4448635, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4446670..4448635, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Seminal fluid protein 24F Neighboring gene uncharacterized protein Neighboring gene modifier of rpr and grim, ubiquitously expressed Neighboring gene Elongator complex protein 3 Neighboring gene uncharacterized protein Neighboring gene tRNA Selenocysteine associated protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons. Etter PD, et al. BMC Neurosci, 2005 Jun 2. PMID 15932641, Free PMC Article
    2. Glia instruct axon regeneration via a ternary modulation of neuronal calcium channels in Drosophila. Trombley S, et al. Nat Commun, 2023 Oct 14. PMID 37838791, Free PMC Article
    3. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article
    4. Drosophila melanogaster as a genetic model system to study neurotransmitter transporters. Martin CA, et al. Neurochem Int, 2014 Jul. PMID 24704795, Free PMC Article
    5. A high throughput screen to identify secreted and transmembrane proteins involved in Drosophila embryogenesis. Kopczynski CC, et al. Proc Natl Acad Sci U S A, 1998 Aug 18. PMID 9707585, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ATP transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    major facilitator superfamily transporter 18
    Names
    CG15438-PA
    MFS18-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4446670..4448635 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134991.3 → NP_608835.1  major facilitator superfamily transporter 18 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608835.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQZ7
      Related
      FBpp0077146
      Conserved Domains (2) summary
      cd06174
      Location:30 → 432
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam07690
      Location:32 → 397
      MFS_1; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQZ7 Q9VQZ7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools