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    cni cornichon [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34967, updated on 9-Dec-2024

    Summary

    Official Symbol
    cniprovided by FlyBase
    Official Full Name
    cornichonprovided by FlyBase
    Primary source
    FLYBASE:FBgn0000339
    Locus tag
    Dmel_CG5855
    See related
    AllianceGenome:FB:FBgn0000339
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-35Fe; BG:DS02740.13; CG5855; Cni; Dmel\CG5855; IV; spnG
    Summary
    Predicted to enable signaling receptor binding activity. Involved in dorsal appendage formation; endoplasmic reticulum to Golgi vesicle-mediated transport; and regionalization. Located in endoplasmic reticulum membrane. Is expressed in adult head; adult heart; germarium; and nurse cell. Orthologous to several human genes including CNIH3 (cornichon family AMPA receptor auxiliary protein 3) and CNIH1 (cornichon family member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See cni in Genome Data Viewer
    Location:
    35F1-35F1; 2-52 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16309292..16310726, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16309292..16310726, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene crossover suppressor on 2 of Manheim Neighboring gene uncharacterized protein Neighboring gene Syntaxin 5 Neighboring gene fizzy Neighboring gene cactus Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein L4

    Genomic regions, transcripts, and products

    Bibliography

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cornichon
    Names
    CG5855-PA
    CG5855-PB
    CG5855-PC
    cni-PA
    cni-PB
    cni-PC
    spindle-G

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      16309292..16310726 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273566.1NP_001260495.1  cornichon, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260495.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V0S2, P49858, Q53XF2, Q9V423
      UniProtKB/TrEMBL
      M9PDJ6
      Conserved Domains (1) summary
      pfam03311
      Location:7135
      Cornichon; Cornichon protein
    2. NM_165151.2NP_723959.1  cornichon, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723959.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V0S2, P49858, Q53XF2, Q9V423
      UniProtKB/TrEMBL
      M9PDJ6
      Related
      FBpp0080405
      Conserved Domains (1) summary
      pfam03311
      Location:7135
      Cornichon; Cornichon protein
    3. NM_057720.3NP_477068.1  cornichon, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477068.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V0S2, P49858, Q53XF2, Q9V423
      UniProtKB/TrEMBL
      M9PDJ6
      Related
      FBpp0080406
      Conserved Domains (1) summary
      pfam03311
      Location:7135
      Cornichon; Cornichon protein