Mtss1 MTSS I-BAR domain containing 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mtss1provided by MGI
Official Full Name: MTSS I-BAR domain containing 1provided by MGI
Primary source: MGI:MGI:2384818
See related: Ensembl:ENSMUSG00000022353 AllianceGenome:MGI:2384818
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Mim; mKIAA0429; 2310003N14Rik; D130001D01Rik
Summary: Enables actin filament binding activity and identical protein binding activity. Involved in several processes, including cellular response to fluid shear stress; glomerulus morphogenesis; and renal tubule development. Acts upstream of or within several processes, including actin filament polymerization; adherens junction maintenance; and positive regulation of actin filament bundle assembly. Located in adherens junction and cytoplasm. Is expressed in several structures, including central nervous system; metanephros; myotome; sensory organ; and spleen. Used to study non-Hodgkin lymphoma. Orthologous to human MTSS1 (MTSS I-BAR domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in liver adult (RPKM 26.2), CNS E18 (RPKM 25.7) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 15 D1; 15 25.09 cM

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (58813083..58955805, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (58941234..59083956, complement)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1.
Title: Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1.
Metastasis suppressor 1 controls osteoblast differentiation and bone homeostasis through regulating Src-Wnt/beta-catenin signaling.
Title: Metastasis suppressor 1 controls osteoblast differentiation and bone homeostasis through regulating Src-Wnt/β-catenin signaling.
Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness.
Title: Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness.
lncRNA Mtss1 promotes inflammatory responses and secondary brain injury after intracerebral hemorrhage by targeting miR-709 in mice.
Title: lncRNA Mtss1 promotes inflammatory responses and secondary brain injury after intracerebral hemorrhage by targeting miR-709 in mice.
Missing-in-Metastasis/Metastasis Suppressor 1 Regulates B Cell Receptor Signaling, B Cell Metabolic Potential, and T Cell-Independent Immune Responses.
Title: Missing-in-Metastasis/Metastasis Suppressor 1 Regulates B Cell Receptor Signaling, B Cell Metabolic Potential, and T Cell-Independent Immune Responses.
MTSS1's C terminus binds to DAAM1 and paused DAAM1-mediated F-actin polymerization.
Title: MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells.
Mtss1 is a key linker between the actin cytoskeleton and the cell membrane, for the development and maintenance of a paradigmatic neuronal circuit, the cerebellar cortex.
Title: Mtss1 promotes maturation and maintenance of cerebellar neurons via splice variant-specific effects.
Study showed that MTSS1 regulates neurite outgrowth and dendritic arborization in primary neurons in vitro, possibly through a Rac1- and PIP-dependent pathway.
Title: Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures.
role of MIM in the homeostasis of BM cells, including HSPCs, through modulation of the CXCR4/SDF-1 axis and interactions of BM leukocytes with their microenvironments.
Title: MIM regulates the trafficking of bone marrow cells via modulating surface expression of CXCR4.
Identify the inverse-BAR (I-BAR) protein MIM/MTSS1 as a nucleator of dendritic spines. MIM accumulated to future spine initiation sites in a PIP2-dependent manner and deformed the plasma membrane outward into a proto-protrusion via its I-BAR domain.
Title: MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation.

Submit: New GeneRIF Correction See all GeneRIFs (20)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (6) 1 citation
Gene trapped (2)
Targeted (5) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AW524128 (e-PCR)
- UniSTS:261783

AW742793 (e-PCR)
- UniSTS:209090

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables actin binding	IBA Inferred from Biological aspect of Ancestor more info
enables actin binding	IDA Inferred from Direct Assay more info	PubMed
enables actin filament binding	IDA Inferred from Direct Assay more info	PubMed
enables actin monomer binding	ISO Inferred from Sequence Orthology more info
enables actin monomer binding	ISS Inferred from Sequence or Structural Similarity more info
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables phospholipid binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables signaling receptor binding	ISO Inferred from Sequence Orthology more info
enables signaling receptor binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within actin filament organization	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within actin filament polymerization	IDA Inferred from Direct Assay more info	PubMed
involved_in adherens junction maintenance	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within adherens junction maintenance	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within bone mineralization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellular response to fluid shear stress	IDA Inferred from Direct Assay more info	PubMed
involved_in epithelial cell proliferation involved in renal tubule morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in glomerulus morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within in utero embryonic development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within magnesium ion homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within metanephric tubule development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in muscle organ development	NAS Non-traceable Author Statement more info	PubMed
involved_in negative regulation of epithelial cell proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nephron tubule epithelial cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nervous system development	NAS Non-traceable Author Statement more info	PubMed
involved_in plasma membrane organization	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of actin filament bundle assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within positive regulation of actin filament bundle assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in renal tubule morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in actin cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in actin cytoskeleton	ISO Inferred from Sequence Orthology more info
located_in actin cytoskeleton	ISS Inferred from Sequence or Structural Similarity more info
located_in adherens junction	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoplasmic side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein MTSS 1

Names: actin monomer-binding protein; metastasis suppressor 1; metastasis suppressor protein 1; missing in metastasis protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001146180.2 → NP_001139652.1 protein MTSS 1 isoform 2

Status: VALIDATED

Description

Transcript Variant: This variant (2) has multiple differences in 3' coding region, compared to variant 1. These differences result in a shorter isoform (2), compared to isoform 1.

Source sequence(s)

AC109185, AC112945, AC158777

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (3) summary

cd07643
Location:7 → 237

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam03276
Location:579 → 707

Gag_spuma; Spumavirus gag protein

cd22060
Location:714 → 744

WH2_MTSS1; Wiskott Aldrich syndrome homology region 2 (WH2 motif) found in Metastasis suppressor protein 1 (MTSS-1)
NM_001403498.1 → NP_001390427.1 protein MTSS 1 isoform 3

Status: VALIDATED

Source sequence(s)

AC109185, AC112945, AC158777
NM_001403499.1 → NP_001390428.1 protein MTSS 1 isoform 4

Status: VALIDATED

Source sequence(s)

AC109185, AC112945, AC158777
NM_001403500.1 → NP_001390429.1 protein MTSS 1 isoform 5

Status: VALIDATED

Source sequence(s)

AC109185, AC112945, AC158777
NM_001403501.1 → NP_001390430.1 protein MTSS 1 isoform 6

Status: VALIDATED

Source sequence(s)

AC109185, AC112945, AC158777
NM_001403502.1 → NP_001390431.1 protein MTSS 1 isoform 7

Status: VALIDATED

Source sequence(s)

AC109185, AC112945, AC158777
NM_001403503.1 → NP_001390432.1 protein MTSS 1 isoform 8

Status: VALIDATED

Source sequence(s)

AC109185, AC112945, AC158777
NM_001403504.1 → NP_001390433.1 protein MTSS 1 isoform 9

Status: VALIDATED

Source sequence(s)

AC109185, AC112945, AC158777
NM_001403505.1 → NP_001390434.1 protein MTSS 1 isoform 10

Status: VALIDATED

Source sequence(s)

AC109185, AC112945, AC158777
NM_001403506.1 → NP_001390435.1 protein MTSS 1 isoform 11

Status: VALIDATED

Source sequence(s)

AC109185, AC112945, AC158777
NM_001403507.1 → NP_001390436.1 protein MTSS 1 isoform 12

Status: VALIDATED

Source sequence(s)

AC109185, AC112945, AC158777
NM_144800.3 → NP_659049.2 protein MTSS 1 isoform 1

See identical proteins and their annotated locations for NP_659049.2

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

Source sequence(s)

AC109185, AC112945, AC158777

Consensus CDS

CCDS27496.1

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

UniProtKB/TrEMBL

G3X9H7

Related

ENSMUSP00000079239.7, ENSMUST00000080371.8

Conserved Domains (2) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam02205
Location:729 → 754

WH2; WH2 motif

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000081.7 Reference GRCm39 C57BL/6J

Range

58813083..58955805 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030248450.1 → XP_030104310.1 protein MTSS 1 isoform X27

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (2) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam03276
Location:528 → 656

Gag_spuma; Spumavirus gag protein
XM_030248449.1 → XP_030104309.1 protein MTSS 1 isoform X25

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (2) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:330 → 680

PHA03247; large tegument protein UL36; Provisional
XM_011245548.3 → XP_011243850.1 protein MTSS 1 isoform X23

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (2) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:330 → 728

PHA03247; large tegument protein UL36; Provisional
XM_036159298.1 → XP_036015191.1 protein MTSS 1 isoform X11

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (3) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:330 → 745

PHA03247; large tegument protein UL36; Provisional

cd22060
Location:743 → 773

WH2_MTSS1; Wiskott Aldrich syndrome homology region 2 (WH2 motif) found in Metastasis suppressor protein 1 (MTSS-1)
XM_011245543.3 → XP_011243845.1 protein MTSS 1 isoform X7

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (3) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:339 → 765

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:628 → 756

Gag_spuma; Spumavirus gag protein
XM_006520712.4 → XP_006520775.1 protein MTSS 1 isoform X19

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (2) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam03276
Location:583 → 711

Gag_spuma; Spumavirus gag protein
XM_011245545.3 → XP_011243847.1 protein MTSS 1 isoform X13

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (3) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:499 → 768

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:603 → 731

Gag_spuma; Spumavirus gag protein
XM_006520709.4 → XP_006520772.1 protein MTSS 1 isoform X5

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (2) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam03276
Location:633 → 761

Gag_spuma; Spumavirus gag protein
XM_011245542.3 → XP_011243844.1 protein MTSS 1 isoform X3

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (2) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam03276
Location:653 → 781

Gag_spuma; Spumavirus gag protein
XM_006520707.4 → XP_006520770.1 protein MTSS 1 isoform X4

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (2) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam03276
Location:648 → 776

Gag_spuma; Spumavirus gag protein
XM_011245540.3 → XP_011243842.1 protein MTSS 1 isoform X1

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (3) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:564 → 833

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:668 → 796

Gag_spuma; Spumavirus gag protein
XM_030248443.1 → XP_030104303.1 protein MTSS 1 isoform X8

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (3) summary

cd07643
Location:7 → 237

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:335 → 761

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:624 → 752

Gag_spuma; Spumavirus gag protein
XM_011245541.3 → XP_011243843.1 protein MTSS 1 isoform X2

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (3) summary

cd07643
Location:7 → 237

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:560 → 829

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:664 → 792

Gag_spuma; Spumavirus gag protein
XM_030248448.2 → XP_030104308.1 protein MTSS 1 isoform X24

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (2) summary

cd07643
Location:7 → 237

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:326 → 724

PHA03247; large tegument protein UL36; Provisional
XM_017316531.3 → XP_017172020.1 protein MTSS 1 isoform X14

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (3) summary

cd07643
Location:7 → 237

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:495 → 764

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:599 → 727

Gag_spuma; Spumavirus gag protein
XM_011245546.2 → XP_011243848.1 protein MTSS 1 isoform X17

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (3) summary

PHA03247
Location:483 → 752

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:587 → 715

Gag_spuma; Spumavirus gag protein

cl12013
Location:1 → 160

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_011245547.2 → XP_011243849.1 protein MTSS 1 isoform X20

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (3) summary

PHA03247
Location:479 → 748

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:583 → 711

Gag_spuma; Spumavirus gag protein

cl12013
Location:1 → 156

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_011245544.1 → XP_011243846.1 protein MTSS 1 isoform X10

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (3) summary

PHA03247
Location:505 → 774

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:609 → 737

Gag_spuma; Spumavirus gag protein

cl12013
Location:9 → 182

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_017316532.2 → XP_017172021.1 protein MTSS 1 isoform X21

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (2) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam03276
Location:568 → 696

Gag_spuma; Spumavirus gag protein
XM_030248446.2 → XP_030104306.1 protein MTSS 1 isoform X16

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (2) summary

cd07643
Location:7 → 241

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam03276
Location:588 → 716

Gag_spuma; Spumavirus gag protein
XM_006520711.5 → XP_006520774.1 protein MTSS 1 isoform X15

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (3) summary

cd07643
Location:7 → 237

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

PHA03247
Location:326 → 726

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:589 → 717

Gag_spuma; Spumavirus gag protein
XM_006520714.5 → XP_006520777.1 protein MTSS 1 isoform X22

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (2) summary

cd07643
Location:7 → 237

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam03276
Location:564 → 692

Gag_spuma; Spumavirus gag protein
XM_030248452.2 → XP_030104312.1 protein MTSS 1 isoform X30

UniProtKB/TrEMBL

Q6ZQB7

Conserved Domains (2) summary

pfam03276
Location:483 → 611

Gag_spuma; Spumavirus gag protein

cl12013
Location:1 → 156

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_006520717.3 → XP_006520780.1 protein MTSS 1 isoform X29

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (3) summary

PHA03247
Location:249 → 649

PHA03247; large tegument protein UL36; Provisional

pfam03276
Location:512 → 640

Gag_spuma; Spumavirus gag protein

cl12013
Location:1 → 160

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_030248451.2 → XP_030104311.1 protein MTSS 1 isoform X28

UniProtKB/Swiss-Prot

Q8BMM3, Q8R1S4, Q99LB3

Conserved Domains (2) summary

cd07643
Location:7 → 237

I-BAR_IMD_MIM; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis

pfam03276
Location:524 → 652

Gag_spuma; Spumavirus gag protein