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    Dap3 death associated protein 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295238, updated on 3-Dec-2024

    Summary

    Official Symbol
    Dap3provided by RGD
    Official Full Name
    death associated protein 3provided by RGD
    Primary source
    RGD:1305339
    See related
    EnsemblRapid:ENSRNOG00000020373 AllianceGenome:RGD:1305339
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within apoptotic mitochondrial changes. Predicted to be located in mitochondrial matrix and nucleoplasm. Predicted to be part of mitochondrial small ribosomal subunit. Orthologous to human DAP3 (death associated protein 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 101.3), Thymus (RPKM 95.7) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Dap3 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176617151..176645293, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (174319341..174347489, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (188225607..188255324, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene synaptotagmin 11 Neighboring gene gon-4 like Neighboring gene misato mitochondrial distribution and morphology regulator 1 Neighboring gene ASH1 like histone lysine methyltransferase Neighboring gene guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 pseudogene Neighboring gene RUN and SH3 domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic mitochondrial changes ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein mS29
    Names
    28S ribosomal protein S29, mitochondrial

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011950.2NP_001011950.2  small ribosomal subunit protein mS29

      See identical proteins and their annotated locations for NP_001011950.2

      Status: VALIDATED

      Source sequence(s)
      AA964664, BC085878
      UniProtKB/TrEMBL
      A6J6B2, F7EZZ0, Q5U2T0
      Related
      ENSRNOP00000027608.5, ENSRNOT00000027608.9
      Conserved Domains (1) summary
      pfam10236
      Location:97392
      DAP3; Mitochondrial ribosomal death-associated protein 3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      176617151..176645293 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281611.1XP_063137681.1  small ribosomal subunit protein mS29 isoform X3

      UniProtKB/TrEMBL
      A6J6B2, F7EZZ0, Q5U2T0
    2. XM_039102039.2XP_038957967.1  small ribosomal subunit protein mS29 isoform X7

      Conserved Domains (1) summary
      pfam10236
      Location:97299
      DAP3; Mitochondrial ribosomal death-associated protein 3
    3. XM_006232610.5XP_006232672.1  small ribosomal subunit protein mS29 isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZZU0, Q5U2T0
      Related
      ENSRNOP00000084514.1, ENSRNOT00000095668.2
      Conserved Domains (1) summary
      pfam10236
      Location:97362
      DAP3; Mitochondrial ribosomal death-associated protein 3
    4. XM_039102038.2XP_038957966.1  small ribosomal subunit protein mS29 isoform X6

      Conserved Domains (1) summary
      pfam10236
      Location:97279
      DAP3; Mitochondrial ribosomal death-associated protein 3
    5. XM_063281614.1XP_063137684.1  small ribosomal subunit protein mS29 isoform X9

    6. XM_063281612.1XP_063137682.1  small ribosomal subunit protein mS29 isoform X4

      UniProtKB/TrEMBL
      A0A0G2K264
    7. XM_063281613.1XP_063137683.1  small ribosomal subunit protein mS29 isoform X8

    8. XM_063281610.1XP_063137680.1  small ribosomal subunit protein mS29 isoform X2

      UniProtKB/TrEMBL
      A0A0G2K264
    9. XM_063281609.1XP_063137679.1  small ribosomal subunit protein mS29 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K264
      Related
      ENSRNOP00000072121.3, ENSRNOT00000088327.3