Ccdc65 coiled-coil domain containing 65 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ccdc65provided by RGD
Official Full Name: coiled-coil domain containing 65provided by RGD
Primary source: RGD:1595842
See related: EnsemblRapid:ENSRNOG00000058916 AllianceGenome:RGD:1595842
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in axonemal dynein complex assembly; cilium-dependent cell motility; and regulation of cilium movement. Predicted to be located in ciliary basal body. Predicted to be part of axonemal dynein complex. Predicted to be active in axoneme. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 27. Orthologous to human CCDC65 (coiled-coil domain containing 65). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 135.5), Brain (RPKM 35.5) and 5 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q36

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (131736002..131749761)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (129857118..129870803)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (140383395..140397186)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH136372 (e-PCR)
- UniSTS:210362

BE097211 (e-PCR)
- UniSTS:260600

AW522737 (e-PCR)
- UniSTS:243454

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in axonemal dynein complex assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium-dependent cell motility	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cilium movement	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cilium movement	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of axonemal dynein complex	IEA Inferred from Electronic Annotation more info
is_active_in axoneme	IBA Inferred from Biological aspect of Ancestor more info
located_in ciliary basal body	ISO Inferred from Sequence Orthology more info
located_in motile cilium	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dynein regulatory complex subunit 2

Names: coiled-coil domain-containing protein 65

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.