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    CG10527 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37393, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10527provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034583
    Locus tag
    Dmel_CG10527
    See related
    AllianceGenome:FB:FBgn0034583
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10527; FAMeT
    Summary
    Located in cytoplasm. Is expressed in several structures, including adult head; female germline cell; follicle cell; gland; and glial cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10527 in Genome Data Viewer
    Location:
    57B16-57B16; 2-92 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21070368..21072789, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16957873..16960294, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44703 Neighboring gene Chitinase 4 Neighboring gene antisense RNA:CR44704 Neighboring gene Chitinase 9 Neighboring gene Trehalase Neighboring gene Rabaptin-5 Neighboring gene uncharacterized protein Neighboring gene Gar1 ribonucleoprotein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CG10527 plays little, if any, role in juvenile hormone (JH) biosynthesis but may participate in the JH signaling pathway.
      Title: Drosophila CG10527 mutants are resistant to juvenile hormone and its analog methoprene.
    2. Data suggest that FAMeT does not have the appropiate protein domains to serve directly as a FAMeT and cannot enzymatically convert farnesoic cid to methyl farnesoate.
      Title: A putative farnesoic acid O-methyltransferase (FAMeT) orthologue in Drosophila melanogaster (CG10527): relationship to juvenile hormone biosynthesis?
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables farnesoic acid O-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10527-PA
    farnesoic acid O-methyltransferase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21070368..21072789 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137700.4 → NP_611544.1  uncharacterized protein Dmel_CG10527 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611544.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MR08, Q9W2M4
      Related
      FBpp0071470
      Conserved Domains (3) summary
      smart00696
      Location:226 → 296
      DM9; Repeats found in Drosophila proteins
      pfam11901
      Location:180 → 286
      DUF3421; Protein of unknown function (DUF3421)
      pfam12248
      Location:35 → 133
      Methyltransf_FA; Farnesoic acid 0-methyl transferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MR08 Q8MR08
    Q9W2M4 Q9W2M4

    Gene LinkOut

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