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    RpS28b Ribosomal protein S28b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31897, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RpS28bprovided by FlyBase
    Official Full Name
    Ribosomal protein S28bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030136
    Locus tag
    Dmel_CG2998
    See related
    AllianceGenome:FB:FBgn0030136
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2998; Dmel\CG2998; RpS28; RS28_DROME; S28e
    Summary
    A structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA and ribosomal small subunit assembly. Located in cytosolic ribosome. Is expressed in adult heart. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 15 with mandibulofacial dysostosis. Orthologous to human RPS28 (ribosomal protein S28). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpS28b in Genome Data Viewer
    Location:
    8E7-8E7; 1-28 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9554623..9555661)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9448656..9449694)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene lethal (1) G0320 Neighboring gene long non-coding RNA:CR42767 Neighboring gene uncharacterized protein Neighboring gene Cubilin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tissue-specific O-GlcNAcylation profiling identifies substrates in translational machinery in Drosophila mushroom body contributing to olfactory learning. Yu H, et al. Elife, 2024 Apr 15. PMID 38619103, Free PMC Article
    2. Opbp is a new architectural/insulator protein required for ribosomal gene expression. Zolotarev N, et al. Nucleic Acids Res, 2017 Dec 1. PMID 29036346, Free PMC Article
    3. Knockdown of Hsc70-5/mortalin induces loss of synaptic mitochondria in a Drosophila Parkinson's disease model. Zhu JY, et al. PLoS One, 2013. PMID 24386261, Free PMC Article
    4. Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching. Hopes T, et al. Nucleic Acids Res, 2022 Feb 28. PMID 34283226, Free PMC Article
    5. Hundreds of putatively functional small open reading frames in Drosophila. Ladoukakis E, et al. Genome Biol, 2011 Nov 25. PMID 22118156, Free PMC Article

    See all (59) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of cytosolic small ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein S28b
    Names
    CG2998-PA
    CG2998-PB
    RpS28b-PA
    RpS28b-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      9554623..9555661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298130.1 → NP_001285059.1  ribosomal protein S28b, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285059.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9W334
      UniProtKB/TrEMBL
      X2JEM4
      Conserved Domains (1) summary
      cd04457
      Location:8 → 65
      S1_S28E; S28E, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. S28E protein is a component of the 30S ribosomal subunit. S28E is highly conserved among archaea and eukaryotes. S28E may control ...

    2. NM_132340.4 → NP_572568.1  ribosomal protein S28b, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572568.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9W334
      UniProtKB/TrEMBL
      X2JEM4
      Related
      FBpp0071295
      Conserved Domains (1) summary
      cd04457
      Location:8 → 65
      S1_S28E; S28E, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. S28E protein is a component of the 30S ribosomal subunit. S28E is highly conserved among archaea and eukaryotes. S28E may control ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W334.2 Q9W334
    X2JEM4 X2JEM4

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