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    snu snustorr [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43391, updated on 9-Dec-2024

    Summary

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    Official Symbol
    snuprovided by FlyBase
    Official Full Name
    snustorrprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039594
    Locus tag
    Dmel_CG9990
    See related
    AllianceGenome:FB:FBgn0039594
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9990; DmCG9990; Dmel\CG9990; Snu
    Summary
    Predicted to enable ABC-type transporter activity; ATP binding activity; and ATP hydrolysis activity. Involved in cuticle development. Located in apical plasma membrane and cytoplasmic vesicle. Is expressed in several structures, including adult head; embryonic anal pad; embryonic head epidermis; epithelium; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See snu in Genome Data Viewer
    Location:
    98E1-98E2; 3-97 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (28675041..28695939)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24500763..24521661)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Stress induced DNase Neighboring gene huntingtin Neighboring gene Allatostatin A receptor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dysfunction of Oskyddad causes Harlequin-type ichthyosis-like defects in Drosophila melanogaster. Wang Y, et al. PLoS Genet, 2020 Jan. PMID 31929524, Free PMC Article
    2. Characterization of axonal transport defects in Drosophila Huntingtin mutants. Weiss KR, et al. J Neurogenet, 2016 Sep-Dec. PMID 27309588, Free PMC Article
    3. The ABC transporter Snu and the extracellular protein Snsl cooperate in the formation of the lipid-based inward and outward barrier in the skin of Drosophila. Zuber R, et al. Eur J Cell Biol, 2018 Mar. PMID 29306642
    4. Characterization of the Drosophila ortholog of the human Usher Syndrome type 1G protein sans. Demontis F, et al. PLoS One, 2009. PMID 19270738, Free PMC Article
    5. Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. Zhang S, et al. Dis Model Mech, 2009 May-Jun. PMID 19380309, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cuticle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasmic vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    snustorr
    Names
    CG9990-PA
    CG9990-PB
    CG9990-PD
    CG9990-PE
    CG9990-PF
    CG9990-PG
    snu-PA
    snu-PB
    snu-PD
    snu-PE
    snu-PF
    snu-PG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      28675041..28695939
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143371.2 → NP_651628.1  snustorr, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651628.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VAU1
      Related
      FBpp0084677
      Conserved Domains (5) summary
      cd03230
      Location:74 → 286
      ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
      COG1136
      Location:73 → 290
      LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
      cl19580
      Location:427 → 474
      pip_yhgE_Nterm; YhgE/Pip N-terminal domain
      pfam01061
      Location:601 → 769
      ABC2_membrane; ABC-2 type transporter
      pfam12698
      Location:429 → 801
      ABC2_membrane_3; ABC-2 family transporter protein

    2. NM_170376.1 → NP_733255.1  snustorr, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733255.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IMM1
      Related
      FBpp0084678, FBtr0085309
      Conserved Domains (5) summary
      cd03230
      Location:43 → 255
      ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
      COG1136
      Location:42 → 259
      LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
      cl19580
      Location:396 → 443
      pip_yhgE_Nterm; YhgE/Pip N-terminal domain
      pfam01061
      Location:570 → 738
      ABC2_membrane; ABC-2 type transporter
      pfam12698
      Location:398 → 770
      ABC2_membrane_3; ABC-2 family transporter protein

    3. NM_001202376.1 → NP_001189305.1  snustorr, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189305.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JD13
      Conserved Domains (4) summary
      cd03230
      Location:43 → 255
      ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
      COG1136
      Location:42 → 259
      LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
      pfam01061
      Location:556 → 724
      ABC2_membrane; ABC-2 type transporter
      pfam12698
      Location:386 → 756
      ABC2_membrane_3; ABC-2 family transporter protein

    4. NM_001276111.1 → NP_001263040.1  snustorr, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001263040.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHS4
      Conserved Domains (4) summary
      cd03230
      Location:32 → 244
      ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
      COG1136
      Location:31 → 248
      LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
      pfam01061
      Location:557 → 725
      ABC2_membrane; ABC-2 type transporter
      pfam12698
      Location:387 → 757
      ABC2_membrane_3; ABC-2 family transporter protein

    5. NM_001260422.1 → NP_001247351.1  snustorr, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247351.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B9EQW2
      Conserved Domains (4) summary
      cd03230
      Location:43 → 255
      ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
      COG1136
      Location:42 → 259
      LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
      pfam01061
      Location:568 → 736
      ABC2_membrane; ABC-2 type transporter
      pfam12698
      Location:398 → 768
      ABC2_membrane_3; ABC-2 family transporter protein

    6. NM_001260421.1 → NP_001247350.1  snustorr, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247350.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K7B3
      Conserved Domains (5) summary
      cd03230
      Location:32 → 244
      ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
      COG1136
      Location:31 → 248
      LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
      cl19580
      Location:385 → 432
      pip_yhgE_Nterm; YhgE/Pip N-terminal domain
      pfam01061
      Location:559 → 727
      ABC2_membrane; ABC-2 type transporter
      pfam12698
      Location:387 → 759
      ABC2_membrane_3; ABC-2 family transporter protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4JD13 A0A0B4JD13
    A0A0B4K7B3 A0A0B4K7B3
    A0A0B4KHS4 A0A0B4KHS4
    B9EQW2 B9EQW2
    Q86LC8 Q86LC8
    Q8IMM1 Q8IMM1
    Q9VAU1 Q9VAU1

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