Gyc89Db Guanylyl cyclase at 89Db [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Gyc89Dbprovided by FlyBase
Official Full Name: Guanylyl cyclase at 89Dbprovided by FlyBase
Primary source: FLYBASE:FBgn0038436
Locus tag: Dmel_CG14886
See related: AllianceGenome:FB:FBgn0038436
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG14886; Dmel\CG14886; Gyc-89Db
Summary: Enables enzyme binding activity; guanylate cyclase activity; and protein heterodimerization activity. Involved in several processes, including nitric oxide-cGMP-mediated signaling; response to hyperoxia; and response to hypoxia. Part of guanylate cyclase complex, soluble. Is expressed in several structures, including anterior wing margin; brain; external sensory organ; labellum; and tarsal segment. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (16477110..16481070)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (12302832..12306792)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables enzyme binding	IPI Inferred from Physical Interaction more info	PubMed
enables guanylate cyclase activity	IBA Inferred from Biological aspect of Ancestor more info
enables guanylate cyclase activity	IDA Inferred from Direct Assay more info	PubMed
enables guanylate cyclase activity	IEA Inferred from Electronic Annotation more info
enables heme binding	IEA Inferred from Electronic Annotation more info
enables protein heterodimerization activity	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in cGMP biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in cGMP-mediated signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in cGMP-mediated signaling	IDA Inferred from Direct Assay more info	PubMed
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info
involved_in nitric oxide-cGMP-mediated signaling	IDA Inferred from Direct Assay more info	PubMed
involved_in response to hyperoxia	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to hypoxia	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to oxygen levels	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to reactive oxygen species	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
part_of guanylate cyclase complex, soluble	IBA Inferred from Biological aspect of Ancestor more info
part_of guanylate cyclase complex, soluble	IC Inferred by Curator more info	PubMed
part_of guanylate cyclase complex, soluble	IDA Inferred from Direct Assay more info	PubMed

NP_650551.1

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