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    capu cappuccino [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33611, updated on 9-Dec-2024

    Summary

    Official Symbol
    capuprovided by FlyBase
    Official Full Name
    cappuccinoprovided by FlyBase
    Primary source
    FLYBASE:FBgn0000256
    Locus tag
    Dmel_CG3399
    See related
    AllianceGenome:FB:FBgn0000256
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    capp; Capu; CG15420; CG3399; Dmel\CG3399
    Summary
    Enables microtubule binding activity. Involved in actin nucleation and pole plasm RNA localization. Located in cell cortex. Is expressed in several structures, including adult head; dorsal ectoderm; dorsal epidermis primordium; female germline cell; and gut section. Human ortholog(s) of this gene implicated in alcohol dependence and autosomal recessive intellectual developmental disorder 47. Orthologous to several human genes including FMN2 (formin 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See capu in Genome Data Viewer
    Location:
    24C8-24C9; 2-11 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3872646..3902860, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3872646..3902860, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Tubulin tyrosine ligase-like 4B Neighboring gene uncharacterized protein Neighboring gene Centrosomal protein 97kDa Neighboring gene friend of echinoid Neighboring gene Folylpolyglutamate synthase 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables microtubule binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in actin filament IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cappuccino
    Names
    CG3399-PA
    CG3399-PB
    CG3399-PD
    CG3399-PE
    CG3399-PF
    CG3399-PG
    CG3399-PH
    CG3399-PI
    CG3399-PJ
    cappucino
    capu-PA
    capu-PB
    capu-PD
    capu-PE
    capu-PF
    capu-PG
    capu-PH
    capu-PI
    capu-PJ

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3872646..3902860 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144313.2NP_001137785.1  cappuccino, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137785.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z014
      Conserved Domains (1) summary
      smart00498
      Location:459886
      FH2; Formin Homology 2 Domain
    2. NM_164565.2NP_722950.2  cappuccino, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722950.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QD2, Q8IQ12
      Conserved Domains (1) summary
      smart00498
      Location:6161043
      FH2; Formin Homology 2 Domain
    3. NM_001144311.2NP_001137783.1  cappuccino, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137783.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z010, Q5BHU8
      Conserved Domains (1) summary
      smart00498
      Location:8071234
      FH2; Formin Homology 2 Domain
    4. NM_001144312.2NP_001137784.1  cappuccino, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137784.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z011, Q5BHU8
      Conserved Domains (1) summary
      smart00498
      Location:8881315
      FH2; Formin Homology 2 Domain
    5. NM_164566.3NP_722951.1  cappuccino, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722951.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C6TPB3, Q9VQV9
      Related
      FBpp0077200
      Conserved Domains (1) summary
      smart00498
      Location:7341161
      FH2; Formin Homology 2 Domain
    6. NM_001144314.2NP_001137786.1  cappuccino, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137786.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z012, C6TPB3
      Conserved Domains (1) summary
      smart00498
      Location:6341061
      FH2; Formin Homology 2 Domain
    7. NM_001144315.2NP_001137787.1  cappuccino, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137787.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7Z013, C6TPB3
      Conserved Domains (1) summary
      smart00498
      Location:8251252
      FH2; Formin Homology 2 Domain
    8. NM_164567.2NP_722952.1  cappuccino, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722952.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C6TPB3, Q8MRP5
      Related
      FBpp0077201
      Conserved Domains (1) summary
      smart00498
      Location:5761003
      FH2; Formin Homology 2 Domain
    9. NM_057618.3NP_476966.1  cappuccino, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476966.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24120, Q9VQV8
      UniProtKB/TrEMBL
      C6TPB3
      Related
      FBpp0077202
      Conserved Domains (1) summary
      smart00498
      Location:5861013
      FH2; Formin Homology 2 Domain