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    CG5895 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39752, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5895provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036560
    Locus tag
    Dmel_CG5895
    See related
    AllianceGenome:FB:FBgn0036560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5895
    Summary
    Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Orthologous to human PLCXD1 (phosphatidylinositol specific phospholipase C X domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5895 in Genome Data Viewer
    Location:
    72D1-72D1; 3-44 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16035485..16037227)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16028585..16030327)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Death-associated inhibitor of apoptosis 1 Neighboring gene antisense RNA:CR45889 Neighboring gene long non-coding RNA:CR43951

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ISWI-containing NURF complex regulates the output of the canonical Wingless pathway. Song H, et al. EMBO Rep, 2009 Oct. PMID 19713963, Free PMC Article
    2. Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom). Mohan M, et al. Genes Dev, 2010 Mar 15. PMID 20203130, Free PMC Article
    3. Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo. Mosimann C, et al. Cell, 2006 Apr 21. PMID 16630820
    4. Epigenetically heritable alteration of fly development in response to toxic challenge. Stern S, et al. Cell Rep, 2012 May 31. PMID 22832276
    5. Molecular genetic analyses of polytene chromosome region 72A-D in Drosophila melanogaster reveal a gene desert in 72D. Cooper MT, et al. PLoS One, 2011. PMID 21853143, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphoric diester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphoric diester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5895-PA
    CG5895-PC
    NP_001163452.2
    NP_648828.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      16035485..16037227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140571.5 → NP_648828.3  uncharacterized protein Dmel_CG5895, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648828.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      F2FB88, Q8SZA0, Q9VUX4
      Related
      FBpp0075195
      Conserved Domains (1) summary
      cd08622
      Location:148 → 435
      PI-PLCXDc_CG14945_like; Catalytic domain of Drosophila melanogaster CG14945-like proteins similar to phosphatidylinositol-specific phospholipase C, X domain containing

    2. NM_001169981.1 → NP_001163452.2  uncharacterized protein Dmel_CG5895, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163452.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JI10, F2FB88
      Conserved Domains (1) summary
      cd08622
      Location:63 → 350
      PI-PLCXDc_CG14945_like; Catalytic domain of Drosophila melanogaster CG14945-like proteins similar to phosphatidylinositol-specific phospholipase C, X domain containing
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JI10 E1JI10
    Q9VUX4 Q9VUX4

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