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    CG12490 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37623, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12490provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034782
    Locus tag
    Dmel_CG12490
    See related
    AllianceGenome:FB:FBgn0034782
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12490
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12490 in Genome Data Viewer
    Location:
    59B2-59B2; 2-101 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22834647..22836701)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18722170..18724224)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Major Facilitator Superfamily Transporter 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article
    2. Nodal points and complexity of Notch-Ras signal integration. Hurlbut GD, et al. Proc Natl Acad Sci U S A, 2009 Feb 17. PMID 19171888, Free PMC Article
    3. Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size. Bonfini A, et al. Elife, 2021 Sep 23. PMID 34553686, Free PMC Article
    4. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204
    5. Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. Broderick NA, et al. mBio, 2014 May 27. PMID 24865556, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12490-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22834647..22836701
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137878.2 → NP_611722.2  uncharacterized protein Dmel_CG12490 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611722.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      C3KGR2, C5WLR3, Q9W1Z2
      Conserved Domains (2) summary
      cd06174
      Location:54 → 438
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:14 → 450
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W1Z2 Q9W1Z2

    Gene LinkOut

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