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    dbf doublefault [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34462, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dbfprovided by FlyBase
    Official Full Name
    doublefaultprovided by FlyBase
    Primary source
    FLYBASE:FBgn0287630
    Locus tag
    Dmel_CG17098
    See related
    AllianceGenome:FB:FBgn0287630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17098; Dbf; Dmel\CG17098; ms(2)04818
    Summary
    Predicted to enable nucleic acid binding activity and zinc ion binding activity. Is expressed in gonad and testis. Orthologous to human ZMAT3 (zinc finger matrin-type 3); ZMAT4 (zinc finger matrin-type 4); and ZNF346 (zinc finger protein 346). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dbf in Genome Data Viewer
    Location:
    32A2-32A2; 2-43 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10651613..10654499)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10651613..10654499)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44580 Neighboring gene long non-coding RNA:CR45692 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Autosomal mutations affecting Y chromosome loops in Drosophila melanogaster. Ceprani F, et al. BMC Genet, 2008 Apr 11. PMID 18405358, Free PMC Article
    2. Drosophila Doublefault protein coordinates multiple events during male meiosis by controlling mRNA translation. Sechi S, et al. Development, 2019 Nov 18. PMID 31645358, Free PMC Article
    3. Microtubule and Actin Cytoskeletal Dynamics in Male Meiotic Cells of Drosophila melanogaster. Frappaolo A, et al. Cells, 2022 Feb 16. PMID 35203341, Free PMC Article
    4. Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. Castrillon DH, et al. Genetics, 1993 Oct. PMID 8244010, Free PMC Article
    5. Satellite DNA-containing gigantic introns in a unique gene expression program during Drosophila spermatogenesis. Fingerhut JM, et al. PLoS Genet, 2019 May. PMID 31071079, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    doublefault
    Names
    CG17098-PA
    dbf-PA
    double fault

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10651613..10654499
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135586.3 → NP_609430.1  doublefault [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609430.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKS7
      Related
      FBpp0079692
      Conserved Domains (2) summary
      smart00451
      Location:613 → 640
      ZnF_U1; U1-like zinc finger
      pfam12874
      Location:524 → 547
      zf-met; Zinc-finger of C2H2 type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKS7 Q9VKS7

    Gene LinkOut

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