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    CG8944 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32517, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8944provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030680
    Locus tag
    Dmel_CG8944
    See related
    AllianceGenome:FB:FBgn0030680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8944
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in embryonic brain; larval ventral nerve cord; and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8944 in Genome Data Viewer
    Location:
    13E12-13E13; 1-51 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15741343..15746231, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15635376..15640264, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Chaperonin containing TCP1 subunit 6 Neighboring gene Mevalonate diphosphate decarboxylase Neighboring gene GTPase regulator associated with FAK

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of Drosophila MicroRNA targets. Stark A, et al. PLoS Biol, 2003 Dec. PMID 14691535, Free PMC Article
    2. A GATA/RUNX cis-regulatory module couples Drosophila blood cell commitment and differentiation into crystal cells. Ferjoux G, et al. Dev Biol, 2007 May 15. PMID 17418114
    3. Gene regulatory networks controlling hematopoietic progenitor niche cell production and differentiation in the Drosophila lymph gland. Tokusumi Y, et al. PLoS One, 2012. PMID 22911822, Free PMC Article
    4. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Dunn JG, et al. Elife, 2013 Dec 3. PMID 24302569, Free PMC Article
    5. Transcription factor networks in Drosophila melanogaster. Rhee DY, et al. Cell Rep, 2014 Sep 25. PMID 25242320, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8944-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15741343..15746231 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132837.3 → NP_573065.1  uncharacterized protein Dmel_CG8944 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573065.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXQ6
      Related
      FBpp0073981
      Conserved Domains (6) summary
      smart00595
      Location:379 → 472
      MADF; subfamily of SANT domain
      sd00017
      Location:666 → 688
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:694 → 716
      zf-C2H2; Zinc finger, C2H2 type
      pfam10545
      Location:259 → 344
      MADF_DNA_bdg; Alcohol dehydrogenase transcription factor Myb/SANT-like
      pfam13465
      Location:708 → 733
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:639 → 712
      zf-C2H2_8; C2H2-type zinc ribbon
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T3I5 Q8T3I5
    Q9VXQ6 Q9VXQ6

    Gene LinkOut

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