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    CG11357 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38561, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11357provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035558
    Locus tag
    Dmel_CG11357
    See related
    AllianceGenome:FB:FBgn0035558
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GM04393; dbeta3GnT; Dmel\CG11357; GalT2
    Summary
    Predicted to enable UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in membrane. Predicted to be active in Golgi membrane. Is expressed in adult head and wing disc. Orthologous to human B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11357 in Genome Data Viewer
    Location:
    64B9-64B9; 3-12 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4542051..4553457)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4542051..4553457)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis. Schwientek T, et al. J Biol Chem, 2002 Sep 6. PMID 12130651
    2. A brain-wide form of presynaptic active zone plasticity orchestrates resilience to brain aging in Drosophila. Huang S, et al. PLoS Biol, 2022 Dec. PMID 36469518, Free PMC Article
    3. A genetic screen for olfactory habituation mutations in Drosophila: analysis of novel foraging alleles and an underlying neural circuit. Eddison M, et al. PLoS One, 2012. PMID 23284741, Free PMC Article
    4. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Hollien J, et al. Science, 2006 Jul 7. PMID 16825573
    5. Post-transcriptional repression of the Drosophila midkine and pleiotrophin homolog miple by HOW is essential for correct mesoderm spreading. Toledano-Katchalski H, et al. Development, 2007 Oct. PMID 17728343

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11357-PA
    CG11357-PB
    CG11357-PC
    CG11357-PD
    NP_001097505.1
    NP_001097506.1
    NP_001246626.1
    NP_647916.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4542051..4553457
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259697.2 → NP_001246626.1  uncharacterized protein Dmel_CG11357, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246626.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZA6
      Conserved Domains (1) summary
      cl21608
      Location:148 → 347
      Galactosyl_T; Galactosyltransferase

    2. NM_001104036.3 → NP_001097506.1  uncharacterized protein Dmel_CG11357, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097506.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZA6
      Conserved Domains (1) summary
      cl21608
      Location:148 → 347
      Galactosyl_T; Galactosyltransferase

    3. NM_139659.3 → NP_647916.1  uncharacterized protein Dmel_CG11357, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647916.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZA6
      Related
      FBpp0073166
      Conserved Domains (1) summary
      cl21608
      Location:148 → 347
      Galactosyl_T; Galactosyltransferase

    4. NM_001104035.2 → NP_001097505.1  uncharacterized protein Dmel_CG11357, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097505.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZA6
      Conserved Domains (1) summary
      cl21608
      Location:148 → 347
      Galactosyl_T; Galactosyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95SA8 Q95SA8
    Q9VZA6 Q9VZA6

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