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    Cpr76Bc Cuticular protein 76Bc [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40122, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cpr76Bcprovided by FlyBase
    Official Full Name
    Cuticular protein 76Bcprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036880
    Locus tag
    Dmel_CG9295
    See related
    AllianceGenome:FB:FBgn0036880
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9295; DmelCpr76Bc; Dmel\CG9295
    Summary
    Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be located in chitin-based extracellular matrix. Predicted to be active in extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cpr76Bc in Genome Data Viewer
    Location:
    76B6-76B6; 3-45 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19520945..19527272)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19514045..19520372)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cuticular protein 76Ba Neighboring gene Cuticular protein 76Bb Neighboring gene Cuticular protein 76Bd Neighboring gene uncharacterized protein Neighboring gene Dctn1-related Neighboring gene antisense RNA:CR43885

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extensive gene amplification and concerted evolution within the CPR family of cuticular proteins in mosquitoes. Cornman RS, et al. Insect Biochem Mol Biol, 2008 Jun. PMID 18510978, Free PMC Article
    2. dGLYAT modulates Gadd45-mediated JNK activation and cell invasion. Xu M, et al. Cell Div, 2022 Aug 6. PMID 35933447, Free PMC Article
    3. A Hopscotch-chromatin connection. Betz A, et al. Nat Genet, 2006 Sep. PMID 16941005
    4. Molecular analysis of flies selected for aggressive behavior. Dierick HA, et al. Nat Genet, 2006 Sep. PMID 16906161
    5. Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. Cooper MT, et al. Genetics, 2010 Jul. PMID 20439780, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of chitin-based larval cuticle ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chitin-based extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cuticular protein 76Bc
    Names
    CG9295-PC
    CG9295-PD
    Cpr76Bc-PC
    Cpr76Bc-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19520945..19527272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275122.1 → NP_001262051.1  cuticular protein 76Bc, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262051.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6L8, Q9VW04
      Conserved Domains (1) summary
      pfam00379
      Location:56 → 108
      Chitin_bind_4; Insect cuticle protein

    2. NM_001104174.2 → NP_001097644.1  cuticular protein 76Bc, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097644.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6L8, Q9VW04
      Conserved Domains (1) summary
      pfam00379
      Location:56 → 108
      Chitin_bind_4; Insect cuticle protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V6L8 Q4V6L8

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