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    CG7304 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39713, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7304provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036527
    Locus tag
    Dmel_CG7304
    See related
    AllianceGenome:FB:FBgn0036527
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7304; dppGalNAcT11
    Summary
    Involved in sexual reproduction. Predicted to be active in Golgi apparatus. Is expressed in adult head. Orthologous to human GALNTL6 (polypeptide N-acetylgalactosaminyltransferase like 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7304 in Genome Data Viewer
    Location:
    71F1-71F1; 3-43 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15679720..15681470)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15672820..15674570)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Eig71Ek Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Polypeptide N-Acetylgalactosaminyltransferase 8 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster. Ten Hagen KG, et al. J Biol Chem, 2003 Sep 12. PMID 12829714
    2. Expression of the UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase family is spatially and temporally regulated during Drosophila development. Tian E, et al. Glycobiology, 2006 Feb. PMID 16251381
    3. Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila. Schwientek T, et al. J Biol Chem, 2002 Jun 21. PMID 11925450
    4. Functional and phylogenetic analyses of a putative Drosophila melanogaster UDP-glycosyltransferase gene. Luque T, et al. Insect Biochem Mol Biol, 2002 Dec. PMID 12429111
    5. Seminal influences: Drosophila Acps and the molecular interplay between males and females during reproduction. Ravi Ram K, et al. Integr Comp Biol, 2007 Sep. PMID 21672851

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables polypeptide N-acetylgalactosaminyltransferase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in oligosaccharide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in sexual reproduction IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7304-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15679720..15681470
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206376.1 → NP_996098.1  uncharacterized protein Dmel_CG7304 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996098.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IA44, Q9VUT4
      Conserved Domains (4) summary
      cd02510
      Location:113 → 417
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      COG0463
      Location:108 → 231
      WcaA; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]
      cd00161
      Location:435 → 548
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:433 → 546
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IA44.1 Q8IA44

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