U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Drsl5 Drosomycin-like 5 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38409, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Drsl5provided by FlyBase
    Official Full Name
    Drosomycin-like 5provided by FlyBase
    Primary source
    FLYBASE:FBgn0035434
    Locus tag
    Dmel_CG10812
    See related
    AllianceGenome:FB:FBgn0035434
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH09576; CG10812; Dmel\CG10812; dmy5; Dro-G; dro5; Dro5; Drs-lG; drsl5
    Summary
    Involved in defense response to fungus. Predicted to be located in extracellular region. Is expressed in adult fat body and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Drsl5 in Genome Data Viewer
    Location:
    63D1-63D1; 3-8 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3316781..3317144)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3316781..3317144)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Drosomycin-like 3 Neighboring gene Drosomycin-like 4 Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class C Neighboring gene uncharacterized protein Neighboring gene Dolichyl-phosphate mannosyltransferase subunit 2 Neighboring gene Striatin interacting protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Transmission of the wMel Wolbachia strain is modulated by its titre and by immune genes in Drosophila melanogaster (Wolbachia density and transmission). Liu XC, et al. J Invertebr Pathol, 2021 May. PMID 33882275
    2. Upregulation of genes belonging to the drosomycin family in diapausing adults of Drosophila triauraria. Daibo S, et al. Gene, 2001 Oct 31. PMID 11707335
    3. Functional role of charged residues in drosomycin, a Drosophila antifungal peptide. Zhang Z, et al. Dev Comp Immunol, 2010 Sep. PMID 20420852
    4. Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster. Yang WY, et al. Gene, 2006 Sep 1. PMID 16824706
    5. Gene expression, antiparasitic activity, and functional evolution of the drosomycin family. Tian C, et al. Mol Immunol, 2008 Sep. PMID 18657321

    See all (75) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Co-option of immune effectors by the hormonal signalling system triggering metamorphosis in Drosophila melanogaster.
      Title: Co-option of immune effectors by the hormonal signalling system triggering metamorphosis in Drosophila melanogaster.
    2. The possible evolutionary fates of drosomycin genes were discussed according to the combining analysis of gene expression pattern, gene structure, and functional divergence of these genes.
      Title: Gene expression divergence and evolutionary analysis of the drosomycin gene family in Drosophila melanogaster.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in defense response to fungus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in defense response to fungus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in extracellular region ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Drosomycin-like 5
    Names
    CG10812-PA
    Drosomycin-like G
    Drsl5-PA
    dro5
    drosmycin-5
    drosomycin
    drosomycin 5
    drosomycin B
    drosomycin-5
    drosomycin-G

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      3316781..3317144
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139546.3 → NP_647803.1  Drosomycin-like 5 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647803.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B0LUZ3, Q9VZR2
      Related
      FBpp0072926
      Conserved Domains (1) summary
      pfam00304
      Location:26 → 68
      Gamma-thionin; Gamma-thionin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2UYJ4 Q2UYJ4
    Q2UYM0 Q2UYM0
    Q2UYN1 Q2UYN1
    Q7JVQ4 Q7JVQ4
    Q9VZR2 Q9VZR2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools