Cfdp1 craniofacial development protein 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cfdp1provided by RGD
Official Full Name: craniofacial development protein 1provided by RGD
Primary source: RGD:735080
See related: EnsemblRapid:ENSRNOG00000019326 AllianceGenome:RGD:735080
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within several processes, including cell adhesion; negative regulation of fibroblast apoptotic process; and regulation of cell shape. Predicted to be located in kinetochore. Predicted to be part of Swr1 complex. Orthologous to human CFDP1 (craniofacial development protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 209.3), Adrenal (RPKM 179.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19q12

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (56627596..56733099, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (39718313..39823824, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (43989596..44078320, complement)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Overcoming off-targets: assessing Western blot signals for Bcnt/Cfdp1, a tentative component of the chromatin remodeling complex.
Title: Overcoming off-targets: assessing Western blot signals for Bcnt/Cfdp1, a tentative component of the chromatin remodeling complex.

Submit: New GeneRIF Correction

General gene information

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Markers

RH129513 (e-PCR)
- UniSTS:212816

RH144415 (e-PCR)
- UniSTS:233660

BQ209669 (e-PCR)
- UniSTS:260544

RH141174 (e-PCR)
- UniSTS:223170

BE110198 (e-PCR)
- UniSTS:245197

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell adhesion	ISO Inferred from Sequence Orthology more info
involved_in chromatin remodeling	IBA Inferred from Biological aspect of Ancestor more info
involved_in fibroblast apoptotic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of fibroblast apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of fibroblast apoptotic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of fibroblast apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cell population proliferation	ISO Inferred from Sequence Orthology more info
involved_in regulation of cell shape	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cell shape	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of Swr1 complex	IBA Inferred from Biological aspect of Ancestor more info
located_in kinetochore	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: craniofacial development protein 1

Names: bucentaur

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199378.5 → NP_955410.1 craniofacial development protein 1

See identical proteins and their annotated locations for NP_955410.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000019

UniProtKB/Swiss-Prot

Q75UQ2

UniProtKB/TrEMBL

A0A8L2QE45, A6IZB0

Related

ENSRNOP00000083789.1, ENSRNOT00000112483.2

Conserved Domains (1) summary

pfam07572
Location:218 → 291

BCNT; Bucentaur or craniofacial development

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086037.1 Reference GRCr8

Range

56627596..56733099 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039097633.2 → XP_038953561.1 craniofacial development protein 1 isoform X1

UniProtKB/TrEMBL

A0A0G2K6H5, A0A8L2QE45

Related

ENSRNOP00000073816.1, ENSRNOT00000089873.3

Conserved Domains (1) summary

pfam07572
Location:221 → 266

BCNT; Bucentaur or craniofacial development