Rsl1d1 ribosomal L1 domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Rsl1d1provided by RGD
Full Name: ribosomal L1 domain containing 1provided by RGD
Primary source: RGD:1359295
See related: EnsemblRapid:ENSRNOG00000069630 AllianceGenome:RGD:1359295
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Csig; Ac1158; Rsl1d1l1
Summary: Predicted to enable mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Predicted to be involved in regulation of apoptotic process and regulation of cellular senescence. Predicted to act upstream of or within regulation of protein localization. Predicted to be located in chromosome. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleolus. Orthologous to human RSL1D1 (ribosomal L1 domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 200.5), Thymus (RPKM 194.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q11

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (4931839..4943726)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (4424868..4436753)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (4375329..4387195)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The proliferation of tenocytes declines with age and is associated with the down-regulation of CSIG.
Title: Decreased proliferation of aging tenocytes is associated with down-regulation of cellular senescence-inhibited gene and up-regulation of p27.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH133814 (e-PCR)
- UniSTS:217097

RH133062 (e-PCR)
- UniSTS:216345

RH139401 (e-PCR)
- UniSTS:221487

RH135149 (e-PCR)
- UniSTS:218426

WI-19180 (e-PCR)
- UniSTS:79190

RH130073 (e-PCR)
- UniSTS:213361

RH128035 (e-PCR)
- UniSTS:211343

RH134253 (e-PCR)
- UniSTS:217535

RH130426 (e-PCR)
- UniSTS:213710

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables mRNA 3'-UTR binding	ISO Inferred from Sequence Orthology more info
enables mRNA 5'-UTR binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in regulation of cellular senescence	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of protein localization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in chromosome	ISO Inferred from Sequence Orthology more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ribosomal L1 domain-containing protein 1

Names: cellular senescence inhibited; ribosomal L1 domain containing 1-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001329198.1 → NP_001316127.1 ribosomal L1 domain-containing protein 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000010

UniProtKB/TrEMBL

A0A0G2JY68

Related

ENSRNOP00000070538.2, ENSRNOT00000084043.3

Conserved Domains (2) summary

PTZ00449
Location:315 → 447

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

pfam00687
Location:48 → 257

Ribosomal_L1; Ribosomal protein L1p/L10e family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086028.1 Reference GRCr8

Range

4931839..4943726

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001008876.2: Suppressed sequence

Description

NM_001008876.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.