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    Prr36 proline rich 36 [ Mus musculus (house mouse) ]

    Gene ID: 73072, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Prr36provided by MGI
    Official Full Name
    proline rich 36provided by MGI
    Primary source
    MGI:MGI:3605626
    See related
    Ensembl:ENSMUSG00000064125 AllianceGenome:MGI:3605626
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Is expressed in cerebral cortex intermediate zone and genitourinary system. Orthologous to human PRR36 (proline rich 36). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in whole brain E14.5 (RPKM 13.5), CNS E14 (RPKM 12.7) and 7 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Prr36 in Genome Data Viewer
    Location:
    8 A1.1; 8 1.98 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (4259478..4267530, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (4209478..4217530, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene CD209g antigen Neighboring gene STARR-seq mESC enhancer starr_20606 Neighboring gene STARR-seq mESC enhancer starr_20608 Neighboring gene RIKEN cDNA 4932443L11 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:4162949-4163058 Neighboring gene STARR-positive B cell enhancer ABC_E355 Neighboring gene ecotropic viral integration site 5 like Neighboring gene STARR-seq mESC enhancer starr_20610 Neighboring gene leucine rich repeat containing 8 family, member E Neighboring gene mitogen-activated protein kinase kinase 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Li J, et al. Nat Neurosci, 2017 Aug. PMID 28671696, Free PMC Article
    2. KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility. Gu J, et al. Cell Death Differ, 2023 Jul. PMID 37142655, Free PMC Article
    3. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
    4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    proline-rich protein 36

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207203.2 → NP_997086.2  proline-rich protein 36

      See identical proteins and their annotated locations for NP_997086.2

      Status: VALIDATED

      Source sequence(s)
      BC068157, CA326920
      Consensus CDS
      CCDS52473.1
      UniProtKB/TrEMBL
      E9PV26, Q6NVE5
      Related
      ENSMUSP00000133114.3, ENSMUST00000168386.9
      Conserved Domains (2) summary
      PHA03247
      Location:434 → 842
      PHA03247; large tegument protein UL36; Provisional
      pfam15363
      Location:1054 → 1098
      DUF4596; Domain of unknown function (DUF4596)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      4259478..4267530 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030243795.1 → XP_030099655.1  proline-rich protein 36 isoform X2

      UniProtKB/TrEMBL
      E9PV26, Q6NVE5
      Conserved Domains (2) summary
      PHA03247
      Location:434 → 842
      PHA03247; large tegument protein UL36; Provisional
      pfam15363
      Location:1054 → 1098
      DUF4596; Domain of unknown function (DUF4596)

    2. XM_011242087.3 → XP_011240389.1  proline-rich protein 36 isoform X2

      See identical proteins and their annotated locations for XP_011240389.1

      UniProtKB/TrEMBL
      E9PV26, Q6NVE5
      Conserved Domains (2) summary
      PHA03247
      Location:434 → 842
      PHA03247; large tegument protein UL36; Provisional
      pfam15363
      Location:1054 → 1098
      DUF4596; Domain of unknown function (DUF4596)

    3. XM_017312982.2 → XP_017168471.1  proline-rich protein 36 isoform X3

      UniProtKB/TrEMBL
      Q6NVE5
      Conserved Domains (3) summary
      PHA03247
      Location:382 → 790
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:10 → 261
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam15363
      Location:1002 → 1046
      DUF4596; Domain of unknown function (DUF4596)

    4. XM_030243796.2 → XP_030099656.1  proline-rich protein 36 isoform X2

      UniProtKB/TrEMBL
      E9PV26, Q6NVE5
      Conserved Domains (2) summary
      PHA03247
      Location:434 → 842
      PHA03247; large tegument protein UL36; Provisional
      pfam15363
      Location:1054 → 1098
      DUF4596; Domain of unknown function (DUF4596)

    5. XM_030243799.2 → XP_030099659.1  proline-rich protein 36 isoform X3

      UniProtKB/TrEMBL
      Q6NVE5
      Conserved Domains (3) summary
      PHA03247
      Location:382 → 790
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:10 → 261
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam15363
      Location:1002 → 1046
      DUF4596; Domain of unknown function (DUF4596)

    6. XM_006508912.5 → XP_006508975.1  proline-rich protein 36 isoform X2

      See identical proteins and their annotated locations for XP_006508975.1

      UniProtKB/TrEMBL
      E9PV26, Q6NVE5
      Conserved Domains (2) summary
      PHA03247
      Location:434 → 842
      PHA03247; large tegument protein UL36; Provisional
      pfam15363
      Location:1054 → 1098
      DUF4596; Domain of unknown function (DUF4596)

    7. XM_036154315.1 → XP_036010208.1  proline-rich protein 36 isoform X3

      UniProtKB/TrEMBL
      Q6NVE5
      Conserved Domains (3) summary
      PHA03247
      Location:382 → 790
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:10 → 261
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam15363
      Location:1002 → 1046
      DUF4596; Domain of unknown function (DUF4596)

    8. XM_030243798.2 → XP_030099658.1  proline-rich protein 36 isoform X3

      UniProtKB/TrEMBL
      Q6NVE5
      Conserved Domains (3) summary
      PHA03247
      Location:382 → 790
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:10 → 261
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam15363
      Location:1002 → 1046
      DUF4596; Domain of unknown function (DUF4596)

    9. XM_006508911.5 → XP_006508974.1  proline-rich protein 36 isoform X2

      See identical proteins and their annotated locations for XP_006508974.1

      UniProtKB/TrEMBL
      E9PV26, Q6NVE5
      Conserved Domains (2) summary
      PHA03247
      Location:434 → 842
      PHA03247; large tegument protein UL36; Provisional
      pfam15363
      Location:1054 → 1098
      DUF4596; Domain of unknown function (DUF4596)

    10. XM_006508914.5 → XP_006508977.1  proline-rich protein 36 isoform X3

      UniProtKB/TrEMBL
      Q6NVE5
      Conserved Domains (3) summary
      PHA03247
      Location:382 → 790
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:10 → 261
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam15363
      Location:1002 → 1046
      DUF4596; Domain of unknown function (DUF4596)

    11. XM_030243797.2 → XP_030099657.1  proline-rich protein 36 isoform X3

      UniProtKB/TrEMBL
      Q6NVE5
      Conserved Domains (3) summary
      PHA03247
      Location:382 → 790
      PHA03247; large tegument protein UL36; Provisional
      PRK07003
      Location:10 → 261
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam15363
      Location:1002 → 1046
      DUF4596; Domain of unknown function (DUF4596)

    12. XM_017312981.3 → XP_017168470.1  proline-rich protein 36 isoform X2

      UniProtKB/TrEMBL
      E9PV26, Q6NVE5
      Conserved Domains (2) summary
      PHA03247
      Location:434 → 842
      PHA03247; large tegument protein UL36; Provisional
      pfam15363
      Location:1054 → 1098
      DUF4596; Domain of unknown function (DUF4596)

    13. XM_017312980.3 → XP_017168469.1  proline-rich protein 36 isoform X1

      UniProtKB/TrEMBL
      Q6NVE5
      Conserved Domains (2) summary
      PHA03247
      Location:456 → 864
      PHA03247; large tegument protein UL36; Provisional
      pfam15363
      Location:1076 → 1120
      DUF4596; Domain of unknown function (DUF4596)

    14. XM_006508913.4 → XP_006508976.1  proline-rich protein 36 isoform X2

      See identical proteins and their annotated locations for XP_006508976.1

      UniProtKB/TrEMBL
      E9PV26, Q6NVE5
      Conserved Domains (2) summary
      PHA03247
      Location:434 → 842
      PHA03247; large tegument protein UL36; Provisional
      pfam15363
      Location:1054 → 1098
      DUF4596; Domain of unknown function (DUF4596)
    Nucleotide Protein Strain
    Heading Accession and Version

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