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    nup85 nucleoporin 85 [ Danio rerio (zebrafish) ]

    Gene ID: 445231, updated on 9-Dec-2024

    Summary

    Official Symbol
    nup85provided by ZNC
    Official Full Name
    nucleoporin 85provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040801-145
    See related
    AllianceGenome:ZFIN:ZDB-GENE-040801-145
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    pcnt1; zgc:100943
    Summary
    Predicted to be a structural constituent of nuclear pore. Predicted to be involved in nephron development; nucleocytoplasmic transport; and positive regulation of DNA-templated transcription. Predicted to act upstream of or within mRNA transport and protein transport. Predicted to be located in nuclear membrane. Predicted to be part of nuclear pore outer ring. Is expressed in ovary. Human ortholog(s) of this gene implicated in nephrotic syndrome type 17. Orthologous to human NUP85 (nucleoporin 85). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
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    Genomic context

    See nup85 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (6443994..6477769)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (6557886..6591661)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene Jupiter microtubule associated homolog 1b Neighboring gene small ubiquitin like modifier 2b Neighboring gene PE-PGRS family protein PE_PGRS33-like Neighboring gene golgi associated, gamma adaptin ear containing, ARF binding protein 3b Neighboring gene sterile alpha motif domain-containing protein 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nephron development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
     
    part_of nuclear pore outer ring IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of nuclear pore outer ring ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nuclear pore complex protein Nup85
    Names
    85 kDa nucleoporin
    nucleoporin NUP85
    pericentrin-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003625.1NP_001003625.1  nuclear pore complex protein Nup85

      See identical proteins and their annotated locations for NP_001003625.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078318
      UniProtKB/Swiss-Prot
      Q6DBY0
      Conserved Domains (1) summary
      pfam07575
      Location:51604
      Nucleopor_Nup85; Nup85 Nucleoporin

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      6443994..6477769
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)